Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1.
about
Tau-tubulin kinaseThe structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitorThe tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.Cdk5 activity in the brain - multiple paths of regulation.The role of tau kinases in Alzheimer's disease.Actin interaction and regulation of cyclin-dependent kinase 5/p35 complex activityTau-tubulin kinase 1 expression, phosphorylation and co-localization with phospho-Ser422 tau in the Alzheimer's disease brain.FGF2 gene transfer restores hippocampal functions in mouse models of Alzheimer's disease and has therapeutic implications for neurocognitive disordersComparison of the neuropsychological mechanisms of 2,6-diisopropylphenol and N-methyl-D-aspartate receptor antagonist against electroconvulsive therapy-induced learning and memory impairment in depressed rats.Progressive effect of beta amyloid peptides accumulation on CA1 pyramidal neurons: a model study suggesting possible treatmentsPLXNA4 is associated with Alzheimer disease and modulates tau phosphorylationDe novo variants in sporadic cases of childhood onset schizophrenia.Increased extrasynaptic GluN2B expression is involved in cognitive impairment after isoflurane anesthesia.Surgical incision-induced nociception causes cognitive impairment and reduction in synaptic NMDA receptor 2B in miceReview: unchained maladie - a reassessment of the role of Ubb(+1) -capped polyubiquitin chains in Alzheimer's disease.TTBK2: a tau protein kinase beyond tau phosphorylation.Insights into plant consciousness from neuroscience, physics and mathematics: a role for quasicrystals?Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1.Calcium signaling in neurodegeneration3,5,6,7,8,3',4'-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus.Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration.Mutations modifying sporadic Alzheimer's disease age of onset.Hypoxia increases Aβ-induced tau phosphorylation by calpain and promotes behavioral consequences in AD transgenic mice.
P2860
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P248
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P2860
Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Spatial learning impairment, e ...... pressing tau-tubulin kinase 1.
@ast
Spatial learning impairment, e ...... pressing tau-tubulin kinase 1.
@en
Spatial learning impairment, e ...... pressing tau-tubulin kinase 1.
@nl
type
label
Spatial learning impairment, e ...... pressing tau-tubulin kinase 1.
@ast
Spatial learning impairment, e ...... pressing tau-tubulin kinase 1.
@en
Spatial learning impairment, e ...... pressing tau-tubulin kinase 1.
@nl
prefLabel
Spatial learning impairment, e ...... pressing tau-tubulin kinase 1.
@ast
Spatial learning impairment, e ...... pressing tau-tubulin kinase 1.
@en
Spatial learning impairment, e ...... pressing tau-tubulin kinase 1.
@nl
P2093
P921
P1476
Spatial learning impairment, e ...... pressing tau-tubulin kinase 1.
@en
P2093
Joshua D Schlautman
Lindsey B Martinez
Michael T Jacobsen
Pawel Ciborowski
Russell J Swan
Satoshi Okuyama
Shannon M Walsh
Shinji Sato
P304
14511-14521
P356
10.1523/JNEUROSCI.3417-08.2008
P407
P577
2008-12-01T00:00:00Z