Varespladib (A-002), a secretory phospholipase A2 inhibitor, reduces atherosclerosis and aneurysm formation in ApoE-/- mice.
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Design of group IIA secreted/synovial phospholipase A(2) inhibitors: an oxadiazolone derivative suppresses chondrocyte prostaglandin E(2) secretionA-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs.The Therapeutic Potential of Anti-Inflammatory Exerkines in the Treatment of AtherosclerosisSecretory phospholipase A2 enzymes as pharmacological targets for treatment of diseaseVarespladib methyl in cardiovascular disease.Group X secretory phospholipase A(2) augments angiotensin II-induced inflammatory responses and abdominal aortic aneurysm formation in apoE-deficient mice.Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell Activation.Emerging drugs for hyperlipidemia.Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytesPrognostic utility of secretory phospholipase A(2) in patients with stable coronary artery disease.Group V secretory phospholipase A2 enhances the progression of angiotensin II-induced abdominal aortic aneurysms but confers protection against angiotensin II-induced cardiac fibrosis in apoE-deficient mice.Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.Secreted phospholipase A2, lipoprotein hydrolysis, and atherosclerosis: integration with lipidomicsInvolvement of the renin-angiotensin system in abdominal and thoracic aortic aneurysms.Secretory phospholipase A2 group IIA modulates insulin sensitivity and metabolism.Inflammatory processes in cardiovascular disease: a route to targeted therapies.Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect?Immune-mediated mechanisms of atherosclerosis and implications for the clinic.Matrix metalloproteinase-2 negatively regulates cardiac secreted phospholipase A2 to modulate inflammation and fever.Evidence for distinct mechanisms of uptake and antitumor activity of secretory phospholipase A2 responsive liposome in prostate cancer.Varespladib inhibits secretory phospholipase A2 in bronchoalveolar lavage of different types of neonatal lung injury.New quinoxalinone inhibitors targeting secreted phospholipase A2 and α-glucosidase.
P2860
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P2860
Varespladib (A-002), a secretory phospholipase A2 inhibitor, reduces atherosclerosis and aneurysm formation in ApoE-/- mice.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Varespladib (A-002), a secreto ...... ysm formation in ApoE-/- mice.
@ast
Varespladib (A-002), a secreto ...... ysm formation in ApoE-/- mice.
@en
Varespladib (A-002), a secreto ...... ysm formation in ApoE-/- mice.
@nl
type
label
Varespladib (A-002), a secreto ...... ysm formation in ApoE-/- mice.
@ast
Varespladib (A-002), a secreto ...... ysm formation in ApoE-/- mice.
@en
Varespladib (A-002), a secreto ...... ysm formation in ApoE-/- mice.
@nl
prefLabel
Varespladib (A-002), a secreto ...... ysm formation in ApoE-/- mice.
@ast
Varespladib (A-002), a secreto ...... ysm formation in ApoE-/- mice.
@en
Varespladib (A-002), a secreto ...... ysm formation in ApoE-/- mice.
@nl
P2093
P1476
Varespladib (A-002), a secreto ...... ysm formation in ApoE-/- mice.
@en
P2093
Charles A Reidy
Colin Hislop
Heather Fraser
Heather L Rick
Joaquim Trias
Kenneth E Gould
Michael L Chouinard
Patrick I Eacho
Robert M Christie
P356
10.1097/FJC.0B013E318195BFBC
P407
P577
2009-01-01T00:00:00Z