TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation. - Wikidata - awgldk - TriplyDB

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

http://www.wikidata.org/entity/Q34926147

about

DUBs, New Members in the Hypoxia Signaling clUb P53 functional abnormality in mesenchymal stem cells promotes osteosarcoma development p73: a Positive or Negative Regulator of Angiogenesis, or Both?Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosis Novel endogenous angiogenesis inhibitors and their therapeutic potential Role of cancer-associated fibroblasts in invasion and metastasis of gastric cancer The different roles of selective autophagic protein degradation in mammalian cells Ultraconserved long non-coding RNA uc.63 in breast cancer Coronary artery calcifications predict long term cardiovascular events in non diabetic Caucasian hemodialysis patients.TAp73 transcriptionally represses BNIP3 expression.Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis.Metabolic pathways regulated by TAp73 in response to oxidative stress Impact of Mediterranean diet on metabolic syndrome, cancer and longevity.Inhibition of cancer antioxidant defense by natural compounds.Role of HSPA1L as a cellular prion protein stabilizer in tumor progression via HIF-1α/GP78 axis.TAp73 upregulates IL-1β in cancer cells: Potential biomarker in lung and breast cancer?Adenovirus-delivered wwox inhibited lung cancer growth in vivo in a mouse model.Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome.A compendium of proteins that interact with HIF-1α.p73 expression is regulated by ribosomal protein RPL26 through mRNA translation and protein stability.The E3 ligase Itch knockout mice show hyperproliferation and wound healing alteration.Novel role of p73 as a regulator of developmental angiogenesis: Implication for cancer therapy.p73 promotes glioblastoma cell invasion by directly activating POSTN (periostin) expression.Antidepressants synergize with chemotherapy against cancer stem cells.Non-oncogenic roles of TAp73: from multiciliogenesis to metabolism.Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer.Cell death-based treatment of neuroblastoma.p73 Regulates Primary Cortical Neuron Metabolism: a Global Metabolic Profile.Clinical implications of the deregulated TP73 isoforms expression in cancer.Inhibition of p53 prevents diabetic cardiomyopathy by preventing early-stage apoptosis and cell senescence, reduced glycolysis, and impaired angiogenesis.Integrin-β4 is a novel transcriptional target of TAp73.ΔNp73 enhances HIF-1α protein stability through repression of the ECV complex.Association between TAp73, p53 and VASH1 expression in lung adenocarcinoma.BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation.p73 Alternative Splicing: Exploring a Biological Role for the C-Terminal Isoforms.TAp73 contributes to the oxidative stress response by regulating protein synthesis.Repair of Critical-Sized Mandible Defects in Aged Rat Using Hypoxia Preconditioned BMSCs with Up-regulation of Hif-1α.Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine

P2860

Q26750882-CCC97112-0654-4D63-8D73-7B6FF83352C5 Q26771603-5A90A7C0-992A-4CBE-AAB1-1C9C51FEC3B2 Q26771853-05E8262D-CE38-46B4-9F80-08D143A7F638 Q26774960-955AF563-60B2-42DF-A9AA-90D918B3762D Q26781297-A0AC4810-6B2D-4EA3-85B1-A31C9A49D6B0 Q26781520-CCE85D6B-1088-4173-8E6A-937801EAA888 Q26785503-8E1BCD0A-C657-4EE0-9517-BC6FA37F3D08 Q33829275-A39D43BD-8158-4BA6-B2EB-7615BB5CB6A1 Q35598557-296B6A35-6CFB-47B2-A277-3C17EF9D4BC7 Q36182254-36A7F978-73B9-4CB8-8253-F4C2F2028C3F Q37053669-505B63FD-A160-4517-9780-1E1536DD9B1A Q37327366-272619C0-CBA7-4F79-8190-11C468B05D0C Q37702835-023950C1-E85B-4F93-B822-FC9FFC42D16F Q37716657-9373385F-5318-4FB2-BB53-ACBCDF23B120 Q38696076-420CBED1-AFE2-43DA-853D-4091EDD43D8C Q38716015-36600911-3371-48AF-B0EA-5BB576B85BCF Q38823735-49489F33-A629-4562-86EE-DA591A5318AC Q38899446-466EF09D-C642-4F3B-B3A7-D35451A34FEC Q39197245-C9703B93-D33B-40B1-B30D-D4850FD7962B Q39204379-C8F4B63A-A946-46DA-B75D-25A7718D420E Q40548355-81BC6B2A-B041-4BDE-BFAB-63556A880FC4 Q40629948-A3546043-93A9-4AFF-9B89-0409B19084CA Q41842526-6E9445B0-9F44-4034-B793-296A4B10A227 Q43089293-A1DF0516-B166-404C-B1B6-7C28AE9F0C9D Q46273393-59760923-8CA7-4C75-B7C0-947C9F444C3B Q47160346-42AD7AD2-0F11-4570-97B6-02B592730B97 Q47839039-DF9AC993-4D37-4371-906F-4DB983530D9B Q47899475-79E79230-C2A0-4FD7-8D82-B32E987C0FB2 Q48136784-332DFA66-94BF-4729-9158-715E36CF6FC8 Q49838551-2CEFFCBB-2A30-4E0F-8111-F131A8A1B665 Q49892600-A05E0166-6887-43A6-A746-6E1FD9D37146 Q52328692-6B66B0A7-B65E-4565-A7D5-736A1B630D54 Q52649723-A2F4B4E9-4D20-48EA-9141-D6E187596728 Q52882453-179E4FC8-1D0A-4ACA-9369-47C1FC17ED17 Q55322510-72319EE8-320A-40F5-B341-1DDBE00E9A2E Q55439098-837DAD8C-F771-4766-A704-97C72A92DADD Q55519460-BA0C1ED6-574A-49E7-8D91-C2D58750EC08 Q57461758-8F5EB2C5-43E4-42FD-AEBD-BB91B3A532B7

P2860

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

http://www.wikidata.org/entity/Q34926147

description

2014 nî lūn-bûn

@nan

2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

@ast

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

@en

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

@nl

type

label

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

@ast

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

@en

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

@nl

prefLabel

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

@ast

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

@en

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

@nl

P1433

Q34926147-C5565EA7-03DA-4FF7-9A4D-E9851C754AE0

P1476

Q34926147-45F26191-E577-4B2E-99AF-7E6E011CB3AD

P2093

Q34926147-26A7A96E-B73C-4027-9A3C-98D0FB851F0B

Q34926147-5660B7FF-39D9-4E82-9C24-DE44D99EA9ED

Q34926147-A98D62FE-D5EA-43C1-B917-754C5C01A0DA

Q34926147-AC542B17-BD8C-4486-8082-7DC4723AB558

Q34926147-C2CE01FE-5DD4-4146-A798-2D03A17BA481

Q34926147-F339D0B7-4415-48BD-B081-69D178D9D3A2

P2860

Q34926147-0A351655-BCC8-4022-A6D5-34C33481F759

Q34926147-0EE054A6-1CAE-4C86-ACA2-CC17D8B8727B

Q34926147-196FDEF0-CBAF-4777-96C5-7C61CB30F72B

Q34926147-1CA1AD84-37A9-4FB0-A38E-533235920564

Q34926147-241936E1-C638-4F64-B0EE-016082C973C0

Q34926147-3B1DBD68-7AAF-4CE3-BD34-965CC0D06CCD

Q34926147-465707A1-A6C2-472D-8FC3-7D5930E2CF51

Q34926147-477CA896-71A6-4FF7-B0A3-0F4A25FAE7EF

Q34926147-4C0758BC-3B21-40A8-A047-C42B8E0E8891

Q34926147-525B7353-109E-4F3C-9BE0-77FF18D8E528

P304

Q34926147-7AADE9F7-C6E1-4B17-86F7-C9E09BFE5499

P31

Q34926147-9B6022E5-7238-40E7-8041-F31174872003

P356

Q34926147-64D51873-D7A7-423C-AB68-D2280C8B008A

P407

Q34926147-23C22FDB-538F-4F33-A691-7679275C3AFD

P433

Q34926147-EBF0597B-4E8D-431E-83E7-B206E2CD7813

P478

Q34926147-AAE03119-69C9-49A8-ACB5-3172B51659F8

P50

Q34926147-13C6C90E-097E-448F-8B6B-217B1328A58F

P577

Q34926147-B3492842-672F-4007-B0DD-A0A736CC8299

P5875

Q34926147-F2C9A399-C4C0-44B3-BEDD-DDEBBD8D0523

P698

Q34926147-1517FFC5-6AAF-4CBB-9D1A-31760819E9F0

P921

Q34926147-0D892E86-6B5A-4DAA-ADC5-250AEBC4815B

P932

Q34926147-04403EC5-7281-48AB-B0C6-3C5F70C79428

P356

PNAS.1410609111

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

@en

P2093

Arnold J Levine

http://www.w3.org/2001/XMLSchema#string

Elke K Markert

http://www.w3.org/2001/XMLSchema#string

Gerry Melino

http://www.w3.org/2001/XMLSchema#string

Richard A Knight

http://www.w3.org/2001/XMLSchema#string

Satoshi Inoue

http://www.w3.org/2001/XMLSchema#string

Tak W Mak

http://www.w3.org/2001/XMLSchema#string

P2860

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53.

MDM2 suppresses p73 function without promoting p73 degradation

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

The ubiquitin system

Mdm2 binds p73 alpha without targeting degradation

HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus

P304

226-231

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1410609111

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

112

http://www.w3.org/2001/XMLSchema#string

P50

P577

2014-12-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

269930110

http://www.w3.org/2001/XMLSchema#string

P698

25535359

http://www.w3.org/2001/XMLSchema#string

P921

P932

4291637

http://www.w3.org/2001/XMLSchema#string