Integrator regulates transcriptional initiation and pause release following activation.
about
Getting up to speed with transcription elongation by RNA polymerase IIIntegrator: surprisingly diverse functions in gene expressionCracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFbFgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.Nipbl Interacts with Zfp609 and the Integrator Complex to Regulate Cortical Neuron Migration.Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.Human mutations in integrator complex subunits link transcriptome integrity to brain development.Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes.Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions.RNA polymerase II pausing can be retained or acquired during activation of genes involved in the epithelial to mesenchymal transition.The host Integrator complex acts in transcription-independent maturation of herpesvirus microRNA 3' ends.snRNA 3' End Processing by a CPSF73-Containing Complex Essential for Development in Arabidopsis.Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathwaysPAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase IIIntegrator mediates the biogenesis of enhancer RNAs.RNA polymerase II pausing as a context-dependent reader of the genome.Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese.Pan-Cancer Mutational and Transcriptional Analysis of the Integrator Complex.Regulation of RNA polymerase II-mediated transcriptional elongation: Implications in human disease.High constitutive activity of a broad panel of housekeeping and tissue-specific cis-regulatory elements depends on a subset of ETS proteinsRegulation of expression of human RNA polymerase II-transcribed snRNA genesO-GlcNAcase Is an RNA Polymerase II Elongation Factor Coupled to Pausing Factors SPT5 and TIF1β.EINCR1 is an EGF inducible lincRNA overexpressed in lung adenocarcinomas.An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides.Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance.Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs.Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone.Nuclear EGFR and Integrator/Super Elongation Complex concurrently binds to Immediate Early Genes for gene transactivation.7SK small nuclear RNA, a multifunctional transcriptional regulatory RNA with gene-specific features.PAF1 regulation of promoter-proximal pause release via enhancer activation.Chromatin dependencies in cancer and inflammation.Global Run-On Sequencing (GRO-Seq).Integrator subunit 4 is a 'Symplekin-like' scaffold that associates with INTS9/11 to form the Integrator cleavage module.Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation.Viral targeting of TFIIB impairs de novo polymerase II recruitment and affects antiviral immunity.Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity
P2860
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P2860
Integrator regulates transcriptional initiation and pause release following activation.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
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2014年學術文章
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name
Integrator regulates transcriptional initiation and pause release following activation.
@ast
Integrator regulates transcriptional initiation and pause release following activation.
@en
Integrator regulates transcriptional initiation and pause release following activation.
@nl
type
label
Integrator regulates transcriptional initiation and pause release following activation.
@ast
Integrator regulates transcriptional initiation and pause release following activation.
@en
Integrator regulates transcriptional initiation and pause release following activation.
@nl
prefLabel
Integrator regulates transcriptional initiation and pause release following activation.
@ast
Integrator regulates transcriptional initiation and pause release following activation.
@en
Integrator regulates transcriptional initiation and pause release following activation.
@nl
P2093
P2860
P1433
P1476
Integrator regulates transcriptional initiation and pause release following activation.
@en
P2093
Alessandro Gardini
Ali Shilatifard
David Baillat
Eric J Wagner
Jill M Marinis
Matteo Cesaroni
Mitchell A Lazar
Ramin Shiekhattar
P2860
P304
P356
10.1016/J.MOLCEL.2014.08.004
P577
2014-09-04T00:00:00Z