NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Galpha.
about
Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architectureEpithelial homeostasisThe intracellular transport and secretion of calumenin-1/2 in living cells.Dynactin-dependent cortical dynein and spherical spindle shape correlate temporally with meiotic spindle rotation in Caenorhabditis elegansMultisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegansAn Asp-CaM complex is required for centrosome-pole cohesion and centrosome inheritance in neural stem cellsMicrocephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindleKLP-7 acts through the Ndc80 complex to limit pole number in C. elegans oocyte meiotic spindle assembly.Searching for signaling balance through the identification of genetic interactors of the Rab guanine-nucleotide dissociation inhibitor gdi-1ASPM regulates Wnt signaling pathway activity in the developing brainThe microtubule-associated protein ASPM regulates spindle assembly and meiotic progression in mouse oocytesMutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germlineASPM and the evolution of cerebral cortical size in a community of New World monkeysDynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation.Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cellsF-actin asymmetry and the endoplasmic reticulum-associated TCC-1 protein contribute to stereotypic spindle movements in the Caenorhabditis elegans embryoCaenorhabditis elegans oocyte meiotic spindle pole assembly requires microtubule severing and the calponin homology domain protein ASPM-1.Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1Kinetochore-independent chromosome segregation driven by lateral microtubule bundlesMicrotubule minus-end regulation at spindle poles by an ASPM-katanin complexA tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large.Distinct molecular cues ensure a robust microtubule-dependent nuclear positioning in the Drosophila oocytePrimary microcephaly: do all roads lead to Rome?Kinesin-dependent transport results in polarized migration of the nucleus in oocytes and inward movement of yolk granules in meiotic embryosThe elegans of spindle assembly.Angelman syndrome protein UBE3A interacts with primary microcephaly protein ASPM, localizes to centrosomes and regulates chromosome segregationNuclear and spindle positioning during oocyte meiosisElevated cyclin B2 expression in invasive breast carcinoma is associated with unfavorable clinical outcomeInsights into molecular features of Venerupis decussata oocytes: a microarray-based study.The spindle assembly function of Caenorhabditis elegans katanin does not require microtubule-severing activity.C. elegans mitotic cyclins have distinct as well as overlapping functions in chromosome segregation.The centrosome and its duplication cycleVisualization of dynein-dependent microtubule gliding at the cell cortex: implications for spindle positioning.A combination of targeted enrichment methodologies for whole-exome sequencing reveals novel pathogenic mutations.A semi-dominant mutation in the general splicing factor SF3a66 causes anterior-posterior axis reversal in one-cell stage C. elegans embryos.CDK-1 inhibits meiotic spindle shortening and dynein-dependent spindle rotation in C. elegans.How signaling between cells can orient a mitotic spindle.Aspm sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice.Mitotic spindle (DIS)orientation and DISease: cause or consequence?Mechanisms of spindle positioning.
P2860
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P248
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P2860
NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Galpha.
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
NuMA-related LIN-5, ASPM-1, ca ...... of cortical LIN-5/GPR/Galpha.
@ast
NuMA-related LIN-5, ASPM-1, ca ...... of cortical LIN-5/GPR/Galpha.
@en
NuMA-related LIN-5, ASPM-1, ca ...... of cortical LIN-5/GPR/Galpha.
@nl
type
label
NuMA-related LIN-5, ASPM-1, ca ...... of cortical LIN-5/GPR/Galpha.
@ast
NuMA-related LIN-5, ASPM-1, ca ...... of cortical LIN-5/GPR/Galpha.
@en
NuMA-related LIN-5, ASPM-1, ca ...... of cortical LIN-5/GPR/Galpha.
@nl
prefLabel
NuMA-related LIN-5, ASPM-1, ca ...... of cortical LIN-5/GPR/Galpha.
@ast
NuMA-related LIN-5, ASPM-1, ca ...... of cortical LIN-5/GPR/Galpha.
@en
NuMA-related LIN-5, ASPM-1, ca ...... of cortical LIN-5/GPR/Galpha.
@nl
P2093
P2860
P50
P356
P1433
P1476
NuMA-related LIN-5, ASPM-1, ca ...... of cortical LIN-5/GPR/Galpha.
@en
P2093
Audrey Perreault
Christian W H Berends
Marc Vidal
Mike Boxem
Tu Nguyen-Ngoc
P2860
P2888
P304
P356
10.1038/NCB1834
P577
2009-02-15T00:00:00Z
P5875
P6179
1052591805