Model-based evaluation of drug-induced QTc prolongation for compounds in early development.
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Modeling and Simulation Approaches for Cardiovascular Function and Their Role in Safety AssessmentAssessment of Interspecies Differences in Drug-Induced QTc Interval Prolongation in Cynomolgus Monkeys, Dogs and Humans.Characterizing QT interval prolongation in early clinical development: a case study with methadone.Pharmacology-based toxicity assessment: towards quantitative risk prediction in humans.Translating QT interval prolongation from conscious dogs to humans.Modelling of drug-induced QT-interval prolongation: estimation approaches and translational opportunities.
P2860
Model-based evaluation of drug-induced QTc prolongation for compounds in early development.
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2015 թվականի հունվարին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
Model-based evaluation of drug ...... ompounds in early development.
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Model-based evaluation of drug ...... ompounds in early development.
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Model-based evaluation of drug ...... ompounds in early development.
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Model-based evaluation of drug ...... ompounds in early development.
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Model-based evaluation of drug ...... ompounds in early development.
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Model-based evaluation of drug ...... ompounds in early development.
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Model-based evaluation of drug ...... ompounds in early development.
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Model-based evaluation of drug ...... ompounds in early development.
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Model-based evaluation of drug ...... ompounds in early development.
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P2093
P2860
P356
P1476
Model-based evaluation of drug ...... ompounds in early development.
@en
P2093
Cardiovascular Safety Project Team and TI Pharma PKPD Platform
Meindert Danhof
Oscar Della Pasqua
Vincent F S Dubois
P2860
P304
P356
10.1111/BCP.12482
P407
P577
2015-01-01T00:00:00Z