Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del-CFTR by a CDK-independent mechanism - Wikidata - awgldk - TriplyDB

Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del-CFTR by a CDK-independent mechanism

Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del-CFTR by a CDK-independent mechanism

http://www.wikidata.org/entity/Q34954019

about

CFTR Modulators: Shedding Light on Precision Medicine for Cystic Fibrosis Harnessing Neutrophil Survival Mechanisms during Chronic Infection by Pseudomonas aeruginosa: Novel Therapeutic Targets to Dampen Inflammation in Cystic Fibrosis In silico search for modifier genes associated with pancreatic and liver disease in Cystic Fibrosis Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis.CFTR pharmacology.Small molecules as therapeutic agents for inborn errors of metabolism.Protein misfolding diseases: prospects of pharmacological treatment.Sodium Channel Trafficking.

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P2860

Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del-CFTR by a CDK-independent mechanism

http://www.wikidata.org/entity/Q34954019

description

2014 nî lūn-bûn

@nan

2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Roscovitine is a proteostasis ...... by a CDK-independent mechanism

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Roscovitine is a proteostasis ...... by a CDK-independent mechanism

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Roscovitine is a proteostasis ...... by a CDK-independent mechanism

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Roscovitine is a proteostasis ...... by a CDK-independent mechanism

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Roscovitine is a proteostasis ...... by a CDK-independent mechanism

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Roscovitine is a proteostasis ...... by a CDK-independent mechanism

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Roscovitine is a proteostasis ...... by a CDK-independent mechanism

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Roscovitine is a proteostasis ...... by a CDK-independent mechanism

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Roscovitine is a proteostasis ...... by a CDK-independent mechanism

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British Journal of Pharmacology

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Roscovitine is a proteostasis ...... by a CDK-independent mechanism

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P2860

Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome

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Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis

Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases

CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis

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4831-4849

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scholarly article

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10.1111/BPH.12859

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