C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs. - Wikidata - awgldk - TriplyDB

C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs.

C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs.

http://www.wikidata.org/entity/Q34958147

about

The corepressor CTBP2 is a coactivator of retinoic acid receptor/retinoid X receptor in retinoic acid signaling Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT)Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis.Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene Targeted disruption of the basic Krüppel-like factor gene (Klf3) reveals a role in adipogenesis The conserved NAD(H)-dependent corepressor CTBP-1 regulates Caenorhabditis elegans life span Use of adenoviral E1A protein to analyze K18 promoter deregulation in colon carcinoma cells discloses a role for CtBP1 and BRCA1.Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer CIBZ, a novel BTB domain-containing protein, is involved in mouse spinal cord injury via mitochondrial pathway independent of p53 gene Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex Interaction with cyclin H/cyclin-dependent kinase 7 (CCNH/CDK7) stabilizes C-terminal binding protein 2 (CtBP2) and promotes cancer cell migration Adenosine monophosphate activated protein kinase (AMPK), a mediator of estradiol-induced apoptosis in long-term estrogen deprived breast cancer cells.Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression.The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS.Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1.CtBP1/BARS is an activator of phospholipase D1 necessary for agonist-induced macropinocytosis.CtBPs promote cell survival through the maintenance of mitotic fidelity.Role of the unique N-terminal domain of CtBP2 in determining the subcellular localisation of CtBP family proteins.HIPK2: a multitalented partner for transcription factors in DNA damage response and development.Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression.Allele-specific KRT1 expression is a complex trait.Interaction of ZEB and histone deacetylase with the PLDLS-binding cleft region of monomeric C-terminal binding protein 2.CtBP1 interacts with Ikaros and modulates pituitary tumor cell survival and response to hypoxia Differential regulation of the α-globin locus by Krüppel-like Factor 3 in erythroid and non-erythroid cells.CtBP2 overexpression promotes tumor cell proliferation and invasion in gastric cancer and is associated with poor prognosis.Homeodomain-interacting protein kinase-2 mediates CtBP phosphorylation and degradation in UV-triggered apoptosis.The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1.Snail family regulation and epithelial mesenchymal transitions in breast cancer progression The mammalian zinc finger transcription factor Krüppel-like factor 3 (KLF3/BKLF).Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance.Conserved catalytic and C-terminal regulatory domains of the C-terminal binding protein corepressor fine-tune the transcriptional response in development.Hypoxia activated EGFR signaling induces epithelial to mesenchymal transition (EMT).Redox sensor CtBP mediates hypoxia-induced tumor cell migration.C-Terminal Binding Protein: A Molecular Link between Metabolic Imbalance and Epigenetic Regulation in Breast Cancer.Opposing oncogenic activities of small DNA tumor virus transforming proteins.A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development The transcriptional corepressor CtBP: a foe of multiple tumor suppressors.Transcriptional down-regulation of Brca1 and E-cadherin by CtBP1 in breast cancer

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P2860

C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs.

http://www.wikidata.org/entity/Q34958147

description

2003 nî lūn-bûn

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2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2003 թվականի ապրիլին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

C-terminal-binding protein cor ...... otic gene expression programs.

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C-terminal-binding protein cor ...... otic gene expression programs.

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C-terminal-binding protein cor ...... otic gene expression programs.

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type

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C-terminal-binding protein cor ...... otic gene expression programs.

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C-terminal-binding protein cor ...... otic gene expression programs.

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C-terminal-binding protein cor ...... otic gene expression programs.

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C-terminal-binding protein cor ...... otic gene expression programs.

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PNAS.0830998100

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Proceedings of the National Academy of Sciences of the United States of America

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C-terminal-binding protein cor ...... otic gene expression programs.

@en

P2093

Jeffrey Hildebrand

http://www.w3.org/2001/XMLSchema#string

Madeleine Grooteclaes

http://www.w3.org/2001/XMLSchema#string

Qinghong Zhang

http://www.w3.org/2001/XMLSchema#string

Quinn Deveraux

http://www.w3.org/2001/XMLSchema#string

Richard H Goodman

http://www.w3.org/2001/XMLSchema#string

Steven M Frisch

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P2860

Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development.

PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family

ZEB represses transcription through interaction with the corepressor CtBP

Disruption of epithelial cell-matrix interactions induces apoptosis

Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase

Epithelial-mesenchymal transitions in tumour progression

FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts

CtBP, an unconventional transcriptional corepressor in development and oncogenesis

Cell cycle and death control: long live Forkheads

Large-scale analysis of the human and mouse transcriptomes.

P304

4568-4573

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scholarly article

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10.1073/PNAS.0830998100

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8

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100

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2003-04-03T00:00:00Z

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10820874

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12676992

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153596

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