HER2-amplified breast cancer: mechanisms of trastuzumab resistance and novel targeted therapies.
about
Long chain fatty Acyl-CoA synthetase 4 is a biomarker for and mediator of hormone resistance in human breast cancerErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancersMLK3 Signaling in Cancer InvasionAberrant Splicing of Estrogen Receptor, HER2, and CD44 Genes in Breast CancerStrategies and Advancement in Antibody-Drug Conjugate Optimization for Targeted Cancer TherapeuticsInvestigating intratumour heterogeneity by single-cell sequencingDurable complete response of metastatic gastric cancer with anti-Met therapy followed by resistance at recurrence.Restoring Lost Anti-HER-2 Th1 Immunity in Breast Cancer: A Crucial Role for Th1 Cytokines in Therapy and PreventionDevelopmental therapeutics for inflammatory breast cancer: Biology and translational directionsUsing high-throughput sequencing transcriptome data for INDEL detection: challenges for cancer drug discovery.Prospective neoadjuvant analysis of PET imaging and mechanisms of resistance to Trastuzumab shows role of HIF1 and autophagy.Prognostic Value of Her2/neu Expression in Gastrointestinal Stromal Tumors: Immunohistochemical Study.Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathwaysIdentification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models.Long-term survivor characteristics in HER2-positive metastatic breast cancer from registHER.Targeting HSP90-HDAC6 Regulating Network Implicates Precision Treatment of Breast Cancer.Metastatic human epidermal growth factor 2 (HER2/neu) amplified breast cancer with acute fulminant hepatitis responding to trastuzumab, pertuzumab and carboplatin.Identification of mTORC2 as a necessary component of HRG/ErbB2-dependent cellular transformationSynergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell linesTherapeutic targeting of integrin αvβ6 in breast cancer.Intratumoral heterogeneity impacts the response to anti-neu antibody therapy.AKT regulates NPM dependent ARF localization and p53mut stability in tumors.The Long-HER study: clinical and molecular analysis of patients with HER2+ advanced breast cancer who become long-term survivors with trastuzumab-based therapy.Enhanced breast cancer therapy with nsPEFs and low concentrations of gemcitabine.Resistance to HER2-targeted therapies: a potential role for FOXM1.Proliferation of colorectal cancer is promoted by two signaling transduction expression patterns: ErbB2/ErbB3/AKT and MET/ErbB3/MAPKHER2 in solid tumors: more than 10 years under the microscope; where are we now?HER2-directed therapy: current treatment options for HER2-positive breast cancer.Successful control of heavily pretreated metastatic gastric cancer with the mTOR inhibitor everolimus (RAD001) in a patient with PIK3CA mutation and pS6 overexpressionContinuous requirement of ErbB2 kinase activity for loss of cell polarity and lumen formation in a novel ErbB2/Neu-driven murine cell line model of metastatic breast cancer.Expression of truncated human epidermal growth factor receptor 2 on circulating tumor cells of breast cancer patients.LncRNA-ATB promotes trastuzumab resistance and invasion-metastasis cascade in breast cancer.Efficacy and tolerability of lapatinib in the management of breast cancerTrastuzumab: updated mechanisms of action and resistance in breast cancerPhase 2 study of MK-2206, an allosteric inhibitor of AKT, as second-line therapy for advanced gastric and gastroesophageal junction cancer: A SWOG cooperative group trial (S1005).Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted TherapiesCould the FDA-approved anti-HIV PR inhibitors be promising anticancer agents? An answer from enhanced docking approach and molecular dynamics analysesCRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.Polymeric oncolytic adenovirus for cancer gene therapy.Requirement for innate immunity and CD90⁺ NK1.1⁻ lymphocytes to treat established melanoma with chemo-immunotherapy.
P2860
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P2860
HER2-amplified breast cancer: mechanisms of trastuzumab resistance and novel targeted therapies.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
HER2-amplified breast cancer: ...... and novel targeted therapies.
@ast
HER2-amplified breast cancer: ...... and novel targeted therapies.
@en
HER2-amplified breast cancer: ...... and novel targeted therapies.
@nl
type
label
HER2-amplified breast cancer: ...... and novel targeted therapies.
@ast
HER2-amplified breast cancer: ...... and novel targeted therapies.
@en
HER2-amplified breast cancer: ...... and novel targeted therapies.
@nl
prefLabel
HER2-amplified breast cancer: ...... and novel targeted therapies.
@ast
HER2-amplified breast cancer: ...... and novel targeted therapies.
@en
HER2-amplified breast cancer: ...... and novel targeted therapies.
@nl
P2860
P356
P1476
HER2-amplified breast cancer: ...... and novel targeted therapies.
@en
P2093
Devika Gajria
Sarat Chandarlapaty
P2860
P304
P356
10.1586/ERA.10.226
P577
2011-02-01T00:00:00Z