Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma - Wikidata - awgldk - TriplyDB

Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma

Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma

http://www.wikidata.org/entity/Q34975272

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Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling FAM129B/MINERVA, a novel adherens junction-associated protein, suppresses apoptosis in HeLa cells 14-3-3ζ interacts with stat3 and regulates its constitutive activation in multiple myeloma cells Use of quantitative mass spectrometric analysis to elucidate the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo.A global protein kinase and phosphatase interaction network in yeast.Post-translational modifications regulate class IIa histone deacetylase (HDAC) function in health and disease Raf kinases in cancer-roles and therapeutic opportunities RSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activation A dynamic view of domain-motif interactions.The coming of age of phosphoproteomics--from large data sets to inference of protein functions How Genetics Has Helped Piece Together the MAPK Signaling Pathway.Clinical targeting of mutated and wild-type protein tyrosine kinases in cancer.Phosphoproteomics for the masses Phosphoproteomics identifies oncogenic Ras signaling targets and their involvement in lung adenocarcinomas.Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3.Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics.Phosphoproteomics in cancer Independent overexpression of the subunits of translation elongation factor complex eEF1H in human lung cancer.193-nm photodissociation of singly and multiply charged peptide anions for acidic proteome characterization.Challenges in plasma membrane phosphoproteomics.Phosphoproteomic analysis of basal and therapy-induced adaptive signaling networks in BRAF and NRAS mutant melanoma.Post-translational modifications of Hsp90 and their contributions to chaperone regulation Phosphoproteomic Analysis of Cell-Based Resistance to BRAF Inhibitor Therapy in Melanoma.RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity.A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells.Regulation of protein kinase D1 activity.Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine Cardiac mitochondrial matrix and respiratory complex protein phosphorylation Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells.EGFR phosphorylates FAM129B to promote Ras activation.Proteomics-based methods for discovery, quantification, and validation of protein-protein interactions.Large-scale discovery of ERK2 substrates identifies ERK-mediated transcriptional regulation by ETV3.Hsp90, an unlikely ally in the war on cancer.Comprehensive quantitative comparison of the membrane proteome, phosphoproteome, and sialiome of human embryonic and neural stem cells.Wnt5a directs polarized calcium gradients by recruiting cortical endoplasmic reticulum to the cell trailing edge.The possible roles of B-cell novel protein-1 (BCNP1) in cellular signalling pathways and in cancer.Quantitative phosphoproteomics strategies for understanding protein kinase-mediated signal transduction pathways.Phosphoproteomic analysis: an emerging role in deciphering cellular signaling in human embryonic stem cells and their differentiated derivatives.

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Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma

http://www.wikidata.org/entity/Q34975272

description

2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Functional proteomics identifi ...... by B-Raf signaling in melanoma

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Functional proteomics identifi ...... by B-Raf signaling in melanoma

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Functional proteomics identifi ...... by B-Raf signaling in melanoma

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Functional proteomics identifi ...... by B-Raf signaling in melanoma

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Functional proteomics identifi ...... by B-Raf signaling in melanoma

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Functional proteomics identifi ...... by B-Raf signaling in melanoma

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prefLabel

Functional proteomics identifi ...... by B-Raf signaling in melanoma

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Functional proteomics identifi ...... by B-Raf signaling in melanoma

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Functional proteomics identifi ...... by B-Raf signaling in melanoma

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J.MOLCEL.2009.03.007

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Functional proteomics identifi ...... by B-Raf signaling in melanoma

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Carrie H Croy

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Chia-Yu Yen

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Elizabeth S Litman

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Eric S Witze

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Hong Wang

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John B Shabb

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Jose G Miranda

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Karen Meyer-Arendt

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Kasey L Couts

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Katheryn A Resing

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P2860

A probability-based approach for high-throughput protein phosphorylation analysis and site localization

Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

Large-scale characterization of HeLa cell nuclear phosphoproteins

Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation

The Brn-2 transcription factor links activated BRAF to melanoma proliferation

Mutations of the BRAF gene in human cancer

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules

Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

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115-131

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10.1016/J.MOLCEL.2009.03.007

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1

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34

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Rebecca Schweppe

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2009-04-01T00:00:00Z

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24273934

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19362540

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phosphorylation

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2735263

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