Growth-factor receptor-bound protein-2 (Grb2) signaling in B cells controls lymphoid follicle organization and germinal center reaction.
about
GRB2 Nucleates T Cell Receptor-Mediated LAT Clusters That Control PLC-γ1 Activation and Cytokine Production.The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclustersNo receptor stands alone: IgG B-cell receptor intrinsic and extrinsic mechanisms contribute to antibody memoryE3 ubiquitin ligase Cbl-b in innate and adaptive immunity.The immunoglobulin tail tyrosine motif upgrades memory-type BCRs by incorporating a Grb2-Btk signalling module.Lymphotoxin α1β2 expression on B cells is required for follicular dendritic cell activation during the germinal center responseE3 ubiquitin ligase Cbl-b negatively regulates C-type lectin receptor-mediated antifungal innate immunityAberrant antibody affinity selection in SHIP-deficient B cells.Besides an ITIM/SHP-1-dependent pathway, CD22 collaborates with Grb2 and plasma membrane calcium-ATPase in an ITIM/SHP-1-independent pathway of attenuation of Ca2+i signal in B cells.Role of Calcium Signaling in B Cell Activation and Biology.A disintegrin and metalloproteinase 10 regulates antibody production and maintenance of lymphoid architecture.Calcium Signaling: From Normal B Cell Development to Tolerance Breakdown and Autoimmunity.Growth factor receptor-bound protein 2 contributes to (hem)immunoreceptor tyrosine-based activation motif-mediated signaling in platelets.Naïve and memory B cells exhibit distinct biochemical responses following BCR engagement.Regulation of B cell functions by the sialic acid-binding receptors siglec-G and CD22.CXCL13 production in B cells via Toll-like receptor/lymphotoxin receptor signaling is involved in lymphoid neogenesis in chronic obstructive pulmonary disease.Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells.
P2860
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P2860
Growth-factor receptor-bound protein-2 (Grb2) signaling in B cells controls lymphoid follicle organization and germinal center reaction.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Growth-factor receptor-bound p ...... and germinal center reaction.
@ast
Growth-factor receptor-bound p ...... and germinal center reaction.
@en
Growth-factor receptor-bound protein-2
@nl
type
label
Growth-factor receptor-bound p ...... and germinal center reaction.
@ast
Growth-factor receptor-bound p ...... and germinal center reaction.
@en
Growth-factor receptor-bound protein-2
@nl
prefLabel
Growth-factor receptor-bound p ...... and germinal center reaction.
@ast
Growth-factor receptor-bound p ...... and germinal center reaction.
@en
Growth-factor receptor-bound protein-2
@nl
P2093
P2860
P356
P1476
Growth-factor receptor-bound p ...... n and germinal center reaction
@en
P2093
Darran G Cronshaw
Guoqiang Fang
Ihn Kyung Jang
Jinping Zhang
Luo-kun Xie
Yongrui Zou
P2860
P304
P356
10.1073/PNAS.1016451108
P407
P50
P577
2011-04-20T00:00:00Z