Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles.

Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles.

Item
http://www.wikidata.org/entity/Q34980516
An in situ autologous tumor vaccination with combined radiation therapy and TLR9 agonist therapyImmune-Stimulatory Dinucleotide at the 5'-End of Oligodeoxynucleotides Is Critical for TLR9-Mediated Immune Responses.A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motifImmunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonistsImmunomodulatory Agents with Antivascular Activity in the Treatment of Non-Small Cell Lung Cancer: Focus on TLR9 Agonists, IMiDs and NGR-TNF.TLR9 agonist protects mice from radiation-induced gastrointestinal syndrome.Novel oligodeoxynucleotide agonists of TLR9 containing N3-Me-dC or N1-Me-dG modifications.TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenograftsProgress in drug development of immunostimulatory CpG oligodeoxynucleotide ligands for TLR9.Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9.Impact of secondary structure of toll-like receptor 9 agonists on interferon alpha induction.Strategy for selecting nanotechnology carriers to overcome immunological and hematological toxicities challenging clinical translation of nucleic acid-based therapeutics.Immunological and hematological toxicities challenging clinical translation of nucleic acid-based therapeutics.Toll-like receptor 9 agonist IMO cooperates with everolimus in renal cell carcinoma by interfering with tumour growth and angiogenesis.Immune modulatory oligonucleotides in the prevention and treatment of OVA-induced eustachian tube dysfunction in rats.Strong immunostimulatory activity of AT-oligodeoxynucleotide requires a six-base loop with a self-stabilized 5'-C...G-3' stem structure.Effect of natural commensal-origin DNA on toll-like receptor 9 (TLR9) signaling cascade, chemokine IL-8 expression, and barrier integritiy of polarized intestinal epithelial cells.
P2860

Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles.

Item
http://www.wikidata.org/entity/Q34980516
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Divergent synthetic nucleotide ...... t cytokine induction profiles.
@ast
Divergent synthetic nucleotide ...... t cytokine induction profiles.
@en
Divergent synthetic nucleotide ...... t cytokine induction profiles.
@nl
type
label
Divergent synthetic nucleotide ...... t cytokine induction profiles.
@ast
Divergent synthetic nucleotide ...... t cytokine induction profiles.
@en
Divergent synthetic nucleotide ...... t cytokine induction profiles.
@nl
prefLabel
Divergent synthetic nucleotide ...... t cytokine induction profiles.
@ast
Divergent synthetic nucleotide ...... t cytokine induction profiles.
@en
Divergent synthetic nucleotide ...... t cytokine induction profiles.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Divergent synthetic nucleotide ...... t cytokine induction profiles.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932