CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists
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Molecular model of cannabis sensitivity in developing neuronal circuitsCannabinergic aminoalkylindoles, including AM678=JWH018 found in 'Spice', examined using drug (Δ(9)-tetrahydrocannabinol) discrimination for ratsHere today, gone tomorrow…and back again? A review of herbal marijuana alternatives (K2, Spice), synthetic cathinones (bath salts), kratom, Salvia divinorum, methoxetamine, and piperazinesBeyond THC: The New Generation of Cannabinoid Designer DrugsAdverse Effects of Synthetic Cannabinoids: Management of Acute Toxicity and WithdrawalNeuropharmacology of New Psychoactive Substances (NPS): Focus on the Rewarding and Reinforcing Properties of Cannabimimetics and Amphetamine-Like StimulantsSynthetic cannabinoids 2015: An update for pediatricians in clinical practiceMarijuana, Spice 'herbal high', and early neural development: implications for rescheduling and legalizationEffects of acute and repeated dosing of the synthetic cannabinoid CP55,940 on intracranial self-stimulation in miceDistinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ(9)-THC: mechanism underlying greater toxicity?The K2/Spice phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products.Dependence Potential of the Synthetic Cannabinoids JWH-073, JWH-081, and JWH-210: In Vivo and In Vitro Approaches.Development of a high-performance liquid chromatography-tandem mass spectrometry method for the identification and quantification of CP-47,497, CP-47,497-C8 and JWH-250 in mouse brain.Cross-substitution of Δ9-tetrahydrocannabinol and JWH-018 in drug discrimination in rats.Direct screening of herbal blends for new synthetic cannabinoids by MALDI-TOF MS.Smart drugs: green shuttle or real drug?Δ9-Tetrahydrocannabinol-like discriminative stimulus effects of compounds commonly found in K2/Spice.Baths salts, spice, and related designer drugs: the science behind the headlines.Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications.Δ(9)-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids in mice and ratsFunctional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands.Neuronal substrates and functional consequences of prenatal cannabis exposure.Synthetic Cannabinoid Receptor Agonists: a heterogeneous class of novel psychoactive substance with emerging risk of psychosis.Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity.An animal model of female adolescent cannabinoid exposure elicits a long-lasting deficit in presynaptic long-term plasticity.Analysis of tolerance and behavioral/physical dependence during chronic CB1 agonist treatment: effects of CB1 agonists, antagonists, and noncannabinoid drugs.Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors.Cannabinoid-related agents in the treatment of anxiety disorders: current knowledge and future perspectives.Spicing things up: synthetic cannabinoids.Fascination and Social Togetherness-Discussions about Spice Smoking on a Swedish Internet Forum.Cannabinoids in disguise: Δ9-tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles.Simultaneous detection of multiple designer drugs in serum, urine, and CSF in a patient with prolonged psychosis.Sphingosine lysolipids in the CNS: endogenous cannabinoid antagonists or a parallel pain modulatory system?Toxicology and management of novel psychoactive drugs.Pharmacological and Toxicological Effects of Synthetic Cannabinoids and Their Metabolites.Pharmacological characterization of repeated administration of the first generation abused synthetic cannabinoid CP47,497.Epidemiology and clinical features of toxicity following recreational use of synthetic cannabinoid receptor agonists: a report from the United Kingdom National Poisons Information Service.Synthetic Cathinone and Cannabinoid Designer Drugs Pose a Major Risk for Public Health.Differential physiological and behavioral cues observed in individuals smoking botanical marijuana versus synthetic cannabinoid drugs.Stratification of Cannabinoid 1 Receptor (CB1R) Agonist Efficacy: Manipulation of CB1R Density through Use of Transgenic Mice Reveals Congruence between In Vivo and In Vitro Assays
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P2860
CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists
description
2011 nî lūn-bûn
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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
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2011年論文
@zh-mo
2011年論文
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2011年论文
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name
CP47,497-C8 and JWH073, common ...... cannabinoid receptor agonists
@ast
CP47,497-C8 and JWH073, common ...... cannabinoid receptor agonists
@en
CP47,497-C8 and JWH073, common ...... cannabinoid receptor agonists
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type
label
CP47,497-C8 and JWH073, common ...... cannabinoid receptor agonists
@ast
CP47,497-C8 and JWH073, common ...... cannabinoid receptor agonists
@en
CP47,497-C8 and JWH073, common ...... cannabinoid receptor agonists
@nl
prefLabel
CP47,497-C8 and JWH073, common ...... cannabinoid receptor agonists
@ast
CP47,497-C8 and JWH073, common ...... cannabinoid receptor agonists
@en
CP47,497-C8 and JWH073, common ...... cannabinoid receptor agonists
@nl
P2093
P2860
P921
P1476
CP47,497-C8 and JWH073, common ...... cannabinoid receptor agonists
@en
P2093
Alex Straiker
Donghoon Lee
Theodore S Widlanski
P2860
P304
P356
10.1016/J.EJPHAR.2011.01.066
P407
P577
2011-02-16T00:00:00Z