Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors.
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Dopamine receptors - IUPHAR Review 13Structure and function of serotonin G protein-coupled receptors.Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid ReceptorStructural Analysis of Chemokine Receptor-Ligand Interactions.Discovery of GPCR ligands for probing signal transduction pathways.Computational studies to predict or explain G protein coupled receptor polypharmacologyMultiple fragment docking and linking in primary and secondary pockets of dopamine receptors.Systematic discovery of molecular probes targeting multiple non-orthosteric and spatially distinct sites in the botulinum neurotoxin subtype A (BoNT/A).Structure-Based Virtual Screening for Dopamine D2 Receptor Ligands as Potential Antipsychotics.Computational Advances for the Development of Allosteric Modulators and Bitopic Ligands in G Protein-Coupled ReceptorsIdentification of Novel Smoothened Ligands Using Structure-Based Docking.New paradigms in GPCR drug discovery.Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery.Structure-based and fragment-based GPCR drug discovery.The receptor concept in 3D: from hypothesis and metaphor to GPCR-ligand structures.Advances and challenges in the search for D2 and D3 dopamine receptor-selective compounds.On the different experimental manifestations of two-state 'induced-fit' binding of drugs to their cellular targetsIdentifying ligands at orphan GPCRs: current status using structure-based approaches.'Partial' competition of heterobivalent ligand binding may be mistaken for allosteric interactions: a comparison of different target interaction models.Synthesis, pharmacological evaluation and molecular modeling studies of triazole containing dopamine D3 receptor ligands.G protein-coupled receptors: computer-aided ligand discovery and computational structural analyses in the 2010s.Chemogenomics knowledgebase and systems pharmacology for hallucinogen target identification-Salvinorin A as a case study.Methods for Virtual Screening of GPCR Targets: Approaches and Challenges.Discovery of new GPCR ligands to illuminate new biology.Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs.Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design.Evolution of dopamine receptors: phylogenetic evidence suggests a later origin of the DRD2l and DRD4rs dopamine receptor gene lineages.Binding kinetics of cariprazine and aripiprazole at the dopamine D receptor
P2860
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P2860
Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors.
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structure-based ligand discove ...... pockets of dopamine receptors.
@ast
Structure-based ligand discove ...... pockets of dopamine receptors.
@en
Structure-based ligand discove ...... pockets of dopamine receptors.
@nl
type
label
Structure-based ligand discove ...... pockets of dopamine receptors.
@ast
Structure-based ligand discove ...... pockets of dopamine receptors.
@en
Structure-based ligand discove ...... pockets of dopamine receptors.
@nl
prefLabel
Structure-based ligand discove ...... pockets of dopamine receptors.
@ast
Structure-based ligand discove ...... pockets of dopamine receptors.
@en
Structure-based ligand discove ...... pockets of dopamine receptors.
@nl
P2093
P2860
P50
P356
P1476
Structure-based ligand discove ...... pockets of dopamine receptors.
@en
P2093
J Robert Lane
Pavel Chubukov
Vadim Cherezov
P2860
P304
P356
10.1124/MOL.113.088054
P577
2013-09-10T00:00:00Z