Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses. - Wikidata - awgldk - TriplyDB

Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses.

Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses.

http://www.wikidata.org/entity/Q34984762

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CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21 CD4 dynamics over a 15 year-period among HIV controllers enrolled in the ANRS French observatory Inhibitory potential of subpopulations of CD8+ T cells in HIV-1-infected elite suppressors Immune responses during spontaneous control of HIV and AIDS: what is the hope for a cure?CD8(+)T-cell-mediated control of HIV-1 and SIV infection.Antibody-Mediated Fcγ Receptor-Based Mechanisms of HIV Inhibition: Recent Findings and New Vaccination Strategies CD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesis HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control.Induction of Potent and Long-Lived Antibody and Cellular Immune Responses in the Genitorectal Mucosa Could be the Critical Determinant of HIV Vaccine Efficacy.Extralymphoid CD8+ T cells resident in tissue from simian immunodeficiency virus SIVmac239{Delta}nef-vaccinated macaques suppress SIVmac239 replication ex vivo.A Subset of Extreme Human Immunodeficiency Virus (HIV) Controllers Is Characterized by a Small HIV Blood Reservoir and a Weak T-Cell Activation Level.Immunological and virological characterization of HIV-1 viremia controllers in the North Region of Brazil.Phenotypic and functional profile of HIV-inhibitory CD8 T cells elicited by natural infection and heterologous prime/boost vaccination Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART.Potential role for HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppression and cytotoxicity in HIV controllers.Association of single nucleotide polymorphisms in the lens epithelium-derived growth factor (LEDGF/p75) with HIV-1 infection outcomes in Brazilian HIV-1+ individuals Early skewed distribution of total and HIV-specific CD8+ T-cell memory phenotypes during primary HIV infection is related to reduced antiviral activity and faster disease progression Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition.Leukocyte immunoglobulin-like receptors maintain unique antigen-presenting properties of circulating myeloid dendritic cells in HIV-1-infected elite controllers Restriction of HIV-1 replication in macrophages and CD4+ T cells from HIV controllers.Immune mechanisms of HIV control.Cytotoxic capacity of SIV-specific CD8(+) T cells against primary autologous targets correlates with immune control in SIV-infected rhesus macaques.Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study CD8 T-cells from most HIV-infected patients lack ex vivo HIV-suppressive capacity during acute and early infection.Relationship of HIV reservoir characteristics with immune status and viral rebound kinetics in an HIV therapeutic vaccine study.Gag-positive reservoir cells are susceptible to HIV-specific cytotoxic T lymphocyte mediated clearance in vitro and can be detected in vivo [corrected]Modulating DNA methylation in activated CD8+ T cells inhibits regulatory T cell-induced binding of Foxp3 to the CD8+ T Cell IL-2 promoter Effector mechanisms in HIV-1 infected elite controllers: highly active immune responses?High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers.HIV controllers with different viral load cutoff levels have distinct virologic and immunologic profiles.Clinical outcome of HIV viraemic controllers and noncontrollers with normal CD4 counts is exclusively determined by antigen-specific CD8+ T-cell-mediated HIV suppression Heterologous prime-boost regimens with a recombinant chimpanzee adenoviral vector and adjuvanted F4 protein elicit polyfunctional HIV-1-specific T-Cell responses in macaques.Long-term control of simian immunodeficiency virus (SIV) in cynomolgus macaques not associated with efficient SIV-specific CD8+ T-cell responses.HIV-1 Tat immunization restores immune homeostasis and attacks the HAART-resistant blood HIV DNA: results of a randomized phase II exploratory clinical trial Broad and persistent Gag-specific CD8+ T-cell responses are associated with viral control but rarely drive viral escape during primary HIV-1 infection A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of an Adjuvanted HIV-1 Gag-Pol-Nef Fusion Protein and Adenovirus 35 Gag-RT-Int-Nef Vaccine in Healthy HIV-Uninfected African Adults.CD8+ TCR Bias and Immunodominance in HIV-1 Infection.For protection from HIV-1 infection, more might not be better: a systematic analysis of HIV Gag epitopes of two alleles associated with different outcomes of HIV-1 infection.TLR agonists and/or IL-15 adjuvanted mucosal SIV vaccine reduced gut CD4⁺ memory T cell loss in SIVmac251-challenged rhesus macaques.

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Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses.

http://www.wikidata.org/entity/Q34984762

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Heterogeneity in HIV suppressi ...... specific CD8 T cell responses.

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Heterogeneity in HIV suppressi ...... specific CD8 T cell responses.

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Heterogeneity in HIV suppressi ...... specific CD8 T cell responses.

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Heterogeneity in HIV suppressi ...... specific CD8 T cell responses.

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Heterogeneity in HIV suppressi ...... specific CD8 T cell responses.

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Heterogeneity in HIV suppressi ...... specific CD8 T cell responses.

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Heterogeneity in HIV suppressi ...... specific CD8 T cell responses.

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Heterogeneity in HIV suppressi ...... specific CD8 T cell responses.

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Heterogeneity in HIV suppressi ...... specific CD8 T cell responses.

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JIMMUNOL.0803928

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Journal of Immunology

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Heterogeneity in HIV suppressi ...... specific CD8 T cell responses.

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ANRS EP36 HIV Controllers Study Group

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Alain Venet

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Alejandra Urrutia

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Faroudy Boufassa

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Jean-François Delfraissy

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Martine Sinet

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So Youn Shin

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Véronique Avettand-Fènoël

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7828-7837

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scholarly article

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10.4049/JIMMUNOL.0803928

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12

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182

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Françoise Barré-Sinoussi

Jean-François Delfraissy

Christine Rouzioux

Asier Sáez-Cirión

Christine Lacabaratz

Gianfranco Pancino

Pierre Versmisse

Olivier Lambotte

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2009-06-01T00:00:00Z

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