Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
about
Tolerance induction in experimental autoimmune encephalomyelitis using non-myeloablative hematopoietic gene therapy with autoantigen.Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation.Tolerization of a type I allergic immune response through transplantation of genetically modified hematopoietic stem cells.Proinsulin is encoded by an RNA splice variant in human blood myeloid cells.Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.Mucosal tolerance to prevent type 1 diabetes: can the outcome be improved in humans?Immunological Basis for Rapid Progression of Diabetes in Older NOD Mouse Recipients Post BM-HSC TransplantationCentral and peripheral autoantigen presentation in immune tolerance.Induction of tolerance to self-antigens using genetically modified bone marrow cells.Gene therapy progress and prospects: gene therapy for diabetes mellitus.Reversing the autoimmune condition: experience with experimental autoimmune gastritis.The insulin A-chain epitope recognized by human T cells is posttranslationally modifiedInsulin as an autoantigen in NOD/human diabetesTolerance to MHC class II disparate allografts through genetic modification of bone marrow.Cellular therapies for type 1 diabetes.Vaccination against self to prevent autoimmune disease: the type 1 diabetes model.The site of allergen expression in hematopoietic cells determines the degree and quality of tolerance induced through molecular chimerismTweaking the immune system: gene therapy-assisted autologous haematopoietic stem cell transplantation as a treatment for autoimmune disease.Breaking T cell tolerance to beta cell antigens by merocytic dendritic cellsThe immunotherapeutic potential of dendritic cells in type 1 diabetes.100 years of hyposensitization: history of allergen-specific immunotherapy (ASIT).Self-antigen expression in the peripheral immune system: roles in self-tolerance and type 1 diabetes pathogenesis.Antigen presenting cell-targeted proinsulin expression converts insulin-specific CD8+ T-cell priming to tolerance in autoimmune-prone NOD mice.Molecular chimerism in IgE-mediated allergy: B-and T-cell tolerance toward highly immunogenic exogenous antigens.Tackling autoimmunity with gene therapyTargeting the CXCR4-CXCL12 axis mobilizes autologous hematopoietic stem cells and prolongs islet allograft survival via programmed death ligand 1.Short-course rapamycin treatment enables engraftment of immunogenic gene-engineered bone marrow under low-dose irradiation to permit long-term immunological tolerance.CD201 and CD27 identify hematopoietic stem and progenitor cells across multiple murine strains independently of Kit and Sca-1.Comparison of transduction efficiency among various lentiviruses containing GFP reporter in bone marrow hematopoietic stem cell transplantation.Re-educating immunity in respiratory allergies: the potential for hematopoietic stem cell-mediated gene therapy.Nonmyeloablative conditioning generates autoantigen-encoding bone marrow that prevents and cures an experimental autoimmune disease.DNA vaccination with an insulin construct and a chimeric protein binding to both CTLA4 and CD40 ameliorates type 1 diabetes in NOD mice.APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD mice.Insulin2 gene (Ins2) transcription by NOD bone marrow-derived cells does not influence autoimmune diabetes development in NOD-Ins2 knockout mice.
P2860
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P2860
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
@ast
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
@en
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
@nl
type
label
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
@ast
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
@en
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
@nl
prefLabel
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
@ast
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
@en
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
@nl
P2093
P2860
P356
P1476
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
@en
P2093
Janine M Ritchie
Leonard C Harrison
Raymond J Steptoe
P2860
P304
P356
10.1172/JCI15995
P407
P577
2003-05-01T00:00:00Z