Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice.
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Microglia centered pathogenesis in ALS: insights in cell interconnectivityProspects for bone marrow cell therapy in amyotrophic lateral sclerosis: how far are we from a clinical treatment?A conceptual revolution in the relationships between the brain and immunity.Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.Novel whole-tissue quantitative assay of nitric oxide levels in Drosophila neuroinflammatory responseEvidence for an early innate immune response in the motor cortex of ALS.Spinal but not cortical microglia acquire an atypical phenotype with high VEGF, galectin-3 and osteopontin, and blunted inflammatory responses in ALS rats.Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS.SOD1(G93A) transgenic mouse CD4(+) T cells mediate neuroprotection after facial nerve axotomy when removed from a suppressive peripheral microenvironment.Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosisPartial suppression of M1 microglia by Janus kinase 2 inhibitor does not protect against neurodegeneration in animal models of amyotrophic lateral sclerosis.Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis.Dual destructive and protective roles of adaptive immunity in neurodegenerative disorders.Brca1 is expressed in human microglia and is dysregulated in human and animal model of ALS.Dysregulated expression of death, stress and mitochondrion related genes in the sciatic nerve of presymptomatic SOD1(G93A) mouse model of Amyotrophic Lateral Sclerosis.Neuronal phagocytosis by inflammatory macrophages in ALS spinal cord: inhibition of inflammation by resolvin D1Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survivalMacrophage-mediated inflammation and glial response in the skeletal muscle of a rat model of familial amyotrophic lateral sclerosis (ALS)Intraspinal bone-marrow cell therapy at pre- and symptomatic phases in a mouse model of amyotrophic lateral sclerosis.Actions of the antihistaminergic clemastine on presymptomatic SOD1-G93A mice ameliorate ALS disease progression.Neuroimmunity dynamics and the development of therapeutic strategies for amyotrophic lateral sclerosis.Genetic ablation of IP3 receptor 2 increases cytokines and decreases survival of SOD1G93A mice.Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase.Immune-mediated mechanisms in the pathoprogression of amyotrophic lateral sclerosis.The multifaceted role of glial cells in amyotrophic lateral sclerosis.Immunology primer for neurosurgeons and neurologists part 2: Innate brain immunity.Cellular therapy to target neuroinflammation in amyotrophic lateral sclerosis.Immunological aspects in amyotrophic lateral sclerosis.Disease origin and progression in amyotrophic lateral sclerosis: an immunology perspective.Comprehensive immune profiling reveals substantial immune system alterations in a subset of patients with amyotrophic lateral sclerosis.CSF concentrations of adipsin and adiponectin in patients with amyotrophic lateral sclerosis.Destination Brain: the Past, Present, and Future of Therapeutic Gene Delivery.S-nitrosylated protein disulfide isomerase contributes to mutant SOD1 aggregates in amyotrophic lateral sclerosis.Therapeutic Strategies Under Development Targeting Inflammatory Mechanisms in Amyotrophic Lateral Sclerosis.The Dual Role of Microglia in ALS: Mechanisms and Therapeutic Approaches.Lessons Learned about Neurodegeneration from Microglia and Monocyte Depletion Studies.P2X7 Receptor Activation Modulates Autophagy in SOD1-G93A Mouse Microglia.Role of Neuroinflammation in Amyotrophic Lateral Sclerosis: Cellular Mechanisms and Therapeutic Implications.The Neurotoxic TAU45-230 Fragment Accumulates in Upper and Lower Motor Neurons in Amyotrophic Lateral Sclerosis Subjects.MicroRNA-125b regulates microglia activation and motor neuron death in ALS.
P2860
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P2860
Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Neuroinflammation modulates di ...... linical responses in ALS mice.
@ast
Neuroinflammation modulates di ...... linical responses in ALS mice.
@en
Neuroinflammation modulates di ...... linical responses in ALS mice.
@nl
type
label
Neuroinflammation modulates di ...... linical responses in ALS mice.
@ast
Neuroinflammation modulates di ...... linical responses in ALS mice.
@en
Neuroinflammation modulates di ...... linical responses in ALS mice.
@nl
prefLabel
Neuroinflammation modulates di ...... linical responses in ALS mice.
@ast
Neuroinflammation modulates di ...... linical responses in ALS mice.
@en
Neuroinflammation modulates di ...... linical responses in ALS mice.
@nl
P2093
P2860
P1476
Neuroinflammation modulates di ...... linical responses in ALS mice.
@en
P2093
Ailing Huang
David R Beers
Jenny S Henkel
Jinghong Wang
Osamu Kano
Weihua Zhao
P2860
P304
P356
10.1016/J.BBI.2010.12.008
P577
2010-12-19T00:00:00Z