RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
about
The mammary cellular hierarchy and breast cancer.Inactivation of RARβ inhibits Wnt1-induced mammary tumorigenesis by suppressing epithelial-mesenchymal transitions.Epigenetic regulation by RARα maintains ligand-independent transcriptional activity.ATRA transcriptionally induces nSMase2 through CBP/p300-mediated histone acetylation.Blocking the PAH2 domain of Sin3A inhibits tumorigenesis and confers retinoid sensitivity in triple negative breast cancerEnhanced expression of retinoic acid receptor alpha (RARA) induces epithelial-to-mesenchymal transition and disruption of mammary acinar structures.Macrophages orchestrate breast cancer early dissemination and metastasis.Left-right analysis of mammary gland development in retinoid X receptor-α+/- mice.Overexpression of EphB4 in the mammary epithelium shifts the differentiation pathway of progenitor cells and promotes branching activity and vascularization.
P2860
Q34396558-BD8B1A53-8CC7-4E8E-AAED-5BEDC88A8FEAQ34564798-B4DDB306-87C6-4D4B-BB50-F3A8B11EED10Q35633556-C1F95162-BBBC-45E5-9401-28261072092CQ36843326-7F7E8261-22C7-48DF-B190-416332BD8DC6Q37536680-3A5F487D-7842-494D-BA3E-BC4D1A1F3928Q38949355-744B6454-8BC8-44C8-984C-2FB72940D8BDQ47217923-B5AAC0AF-690F-4817-BE7F-A5ADA102B0D9Q50478792-A61787EE-5A20-4B06-8AD9-FC41CF63DCACQ54217865-D469620C-5AD9-4F38-A6A8-AEAD44DB8808
P2860
RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
@ast
RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
@en
RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
@nl
type
label
RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
@ast
RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
@en
RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
@nl
prefLabel
RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
@ast
RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
@en
RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
@nl
P2093
P2860
P356
P1476
RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
@en
P2093
Christine Marzan
Eduardo F Farias
Ellen Cohn
Liliana Ossowski
Silvina Bertran
P2860
P2888
P356
10.1186/BCR2724
P577
2010-10-05T00:00:00Z
P5875
P6179
1020416748