Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy. - Wikidata - awgldk - TriplyDB

Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy.

Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy.

http://www.wikidata.org/entity/Q34993085

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Mitochondria, cholesterol and cancer cell metabolism HER2 confers drug resistance of human breast cancer cells through activation of NRF2 by direct interaction Comparative analysis of NRF2-responsive gene expression in AcPC-1 pancreatic cancer cell line Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells The complexity of the Nrf2 pathway: beyond the antioxidant response Cytoprotection "gone astray": Nrf2 and its role in cancer Inhibition of NRF2 by PIK-75 augments sensitivity of pancreatic cancer cells to gemcitabine Mechanistic evaluation of a novel small molecule targeting mitochondria in pancreatic cancer cells Soluble factors from stellate cells induce pancreatic cancer cell proliferation via Nrf2-activated metabolic reprogramming and ROS detoxification Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2.GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and Akt pathway after epirubicin treatment in colon cancer DLD-1 cells.Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2 The complex landscape of pancreatic cancer metabolism Epigenetic DNA methylation of antioxidative stress regulator NRF2 in human prostate cancer The role of the catecholic and the electrophilic moieties of caffeic acid in Nrf2/Keap1 pathway activation in ovarian carcinoma cell lines.Clinical significance of Keap1 and Nrf2 in oral squamous cell carcinoma.Contribution of environment and genetics to pancreatic cancer susceptibility Quantitative evaluation of aldo-keto reductase expression in hepatocellular carcinoma (HCC) cell lines.Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells.Benefits and risks of the hormetic effects of dietary isothiocyanates on cancer prevention.miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells.Keap1 expression has independent prognostic value in pancreatic adenocarcinomas Molecular pathways: Fumarate hydratase-deficient kidney cancer--targeting the Warburg effect in cancer.The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells.The anti-oxidative transcription factor Nuclear factor E2 related factor-2 (Nrf2) counteracts TGF-β1 mediated growth inhibition of pancreatic ductal epithelial cells -Nrf2 as determinant of pro-tumorigenic functions of TGF-β1.NAD(P)H:Quinone Oxidoreductase-1 Expression Sensitizes Malignant Melanoma Cells to the HSP90 Inhibitor 17-AAG Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells.The Relevance of Nrf2 Pathway and Autophagy in Pancreatic Cancer Cells upon Stimulation of Reactive Oxygen Species.NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies.UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis NRF2 and the Phase II Response in Acute Stress Resistance Induced by Dietary Restriction.Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination.Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-AKR1C1 pathway.Brusatol Enhances the Radiosensitivity of A549 Cells by Promoting ROS Production and Enhancing DNA Damage The emerging role of the Nrf2-Keap1 signaling pathway in cancer Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1.Nrf2 inhibition sensitizes cholangiocarcinoma cells to cytotoxic and antiproliferative activities of chemotherapeutic agents.Emerging role of NRF2 in chemoresistance by regulating drug-metabolizing enzymes and efflux transporters.Repression of Nrf2 enhances antitumor effect of 5-fluorouracil and gemcitabine on cholangiocarcinoma cells.

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P2860

Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy.

http://www.wikidata.org/entity/Q34993085

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

@wuu

name

Nrf2 is overexpressed in pancr ...... ell proliferation and therapy.

@ast

Nrf2 is overexpressed in pancr ...... ell proliferation and therapy.

@en

Nrf2 is overexpressed in pancr ...... ell proliferation and therapy.

@nl

type

label

Nrf2 is overexpressed in pancr ...... ell proliferation and therapy.

@ast

Nrf2 is overexpressed in pancr ...... ell proliferation and therapy.

@en

Nrf2 is overexpressed in pancr ...... ell proliferation and therapy.

@nl

prefLabel

Nrf2 is overexpressed in pancr ...... ell proliferation and therapy.

@ast

Nrf2 is overexpressed in pancr ...... ell proliferation and therapy.

@en

Nrf2 is overexpressed in pancr ...... ell proliferation and therapy.

@nl

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Molecular Cancer

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B Kevin Park

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Bryony Lloyd

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Taoufik Nedjadi

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P2860

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

Cancer statistics, 2009

Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group

Adjuvant 5-fluorouracil and folinic acid vs observation for pancreatic cancer: composite data from the ESPAC-1 and -3(v1) trials

Nuclear factor (erythroid-derived 2)-like 2 regulates drug resistance in pancreatic cancer cells.

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