Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases
about
Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular PerspectivesTargeting Strategies for Renal Cell Carcinoma: From Renal Cancer Cells to Renal Cancer Stem CellsConformational ensembles explored dynamically from disordered peptides targeting chemokine receptor CXCR4.A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumorsInhibition of CXCL12/CXCR4 axis as a potential targeted therapy of advanced gastric carcinomaBRAF(V600E) melanoma cells secrete factors that activate stromal fibroblasts and enhance tumourigenicity.The intricate role of CXCR4 in cancer.CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does notIdentification of a distinct population of CD133(+)CXCR4(+) cancer stem cells in ovarian cancerTargeting CXCR4 by a selective peptide antagonist modulates tumor microenvironment and microglia reactivity in a human glioblastoma modelEpigenetically silenced GNG4 inhibits SDF1α/CXCR4 signaling in mesenchymal glioblastomaN-terminal polypeptide derived from vMIP-II exerts its antitumor activity by inhibiting the CXCR4 pathway in human gliomaEmerging therapeutic targets for the treatment of human acute myeloid leukemia (part 1) - gene transcription, cell cycle regulation, metabolism and intercellular communication.Progress toward rationally designed small-molecule peptide and peptidomimetic CXCR4 antagonists.Altered CXCL12 expression reveals a dual role of CXCR4 in osteosarcoma primary tumor growth and metastasis.CXCR4/CXCL12/CXCR7 axis is functional in neuroendocrine tumors and signals on mTOR.SDF-1/CXCR4 promotes F5M2 osteosarcoma cell migration by activating the Wnt/β-catenin signaling pathway.CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells.CXCR4-antagonist Peptide R-liposomes for combined therapy against lung metastasis.CXCR4-CXCL12-CXCR7, TLR2-TLR4, and PD-1/PD-L1 in colorectal cancer liver metastases from neoadjuvant-treated patients.Isolation of Stem-Like Cancer Cells in Primary Endometrial Cancer Using Cell Surface Markers CD133 and CXCR4.Targeting CXCR4 reverts the suppressive activity of T-regulatory cells in renal cancer.When Immune Cells Turn Bad-Tumor-Associated Microglia/Macrophages in Glioma.Design, synthesis, and biological evaluation of CXCR4 ligands.To Explore the Mechanism of the GRM4 Gene in Osteosarcoma by RNA Sequencing and Bioinformatics Approach.Intrinsically disordered amphiphilic peptides as potential targets in drug delivery vehicles
P2860
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P2860
Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Preclinical development of a n ...... d tumors growth and metastases
@ast
Preclinical development of a n ...... d tumors growth and metastases
@en
Preclinical development of a n ...... d tumors growth and metastases
@nl
type
label
Preclinical development of a n ...... d tumors growth and metastases
@ast
Preclinical development of a n ...... d tumors growth and metastases
@en
Preclinical development of a n ...... d tumors growth and metastases
@nl
prefLabel
Preclinical development of a n ...... d tumors growth and metastases
@ast
Preclinical development of a n ...... d tumors growth and metastases
@en
Preclinical development of a n ...... d tumors growth and metastases
@nl
P2093
P2860
P50
P1433
P1476
Preclinical development of a n ...... d tumors growth and metastases
@en
P2093
Andrea Ciarmiello
Caterina Ieranò
Luca Monfregola
Luigi Portella
Maria Neve Polimeno
Pietro Amodeo
Rosamaria Vitale
P2860
P304
P356
10.1371/JOURNAL.PONE.0074548
P407
P50
P577
2013-09-13T00:00:00Z