Insight into the intermolecular recognition mechanism between Keap1 and IKKβ combining homology modelling, protein-protein docking, molecular dynamics simulations and virtual alanine mutation

Insight into the intermolecular recognition mechanism between Keap1 and IKKβ combining homology modelling, protein-protein docking, molecular dynamics simulations and virtual alanine mutation

Item
http://www.wikidata.org/entity/Q34997448
Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseThe Keap1-Nrf2 pathway: promising therapeutic target to counteract ROS-mediated damage in cancers and neurodegenerative diseases.Antihepatocarcinoma Effect of Portulaca oleracea L. in Mice by PI3K/Akt/mTOR and Nrf2/HO-1/NF-κB Pathway.Transcription factors NRF2 and NF-κB are coordinated effectors of the Rho family, GTP-binding protein RAC1 during inflammation.Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405.Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophagesRole of the Nrf2 signaling system in health and disease.Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update.Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001A systematic molecular dynamics approach to the study of peptide Keap1-Nrf2 protein-protein interaction inhibitors and its application to p62 peptides.Investigation of the intermolecular recognition mechanism between the E3 ubiquitin ligase Keap1 and substrate based on multiple substrates analysis.The protective effect of betulinic acid (BA) diabetic nephropathy on streptozotocin (STZ)-induced diabetic rats.
P2860

Insight into the intermolecular recognition mechanism between Keap1 and IKKβ combining homology modelling, protein-protein docking, molecular dynamics simulations and virtual alanine mutation

Item
http://www.wikidata.org/entity/Q34997448
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Insight into the intermolecula ...... s and virtual alanine mutation
@ast
Insight into the intermolecula ...... s and virtual alanine mutation
@en
Insight into the intermolecula ...... s and virtual alanine mutation
@nl
type
label
Insight into the intermolecula ...... s and virtual alanine mutation
@ast
Insight into the intermolecula ...... s and virtual alanine mutation
@en
Insight into the intermolecula ...... s and virtual alanine mutation
@nl
prefLabel
Insight into the intermolecula ...... s and virtual alanine mutation
@ast
Insight into the intermolecula ...... s and virtual alanine mutation
@en
Insight into the intermolecula ...... s and virtual alanine mutation
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Insight into the intermolecula ...... s and virtual alanine mutation
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0075076
P407
P433
P478
P50
P577
P5875
P698
P932