Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.
about
Mechanism-based inactivation of CYP450 enzymes: a case study of lapatinibLapatinib antagonizes multidrug resistance-associated protein 1-mediated multidrug resistance by inhibiting its transport function.Studies on the role of metabolic activation in tyrosine kinase inhibitor-dependent hepatotoxicity: induction of CYP3A4 enhances the cytotoxicity of lapatinib in HepaRG cellsGenetic characterization to improve interpretation and clinical management of hepatotoxicity caused by tyrosine kinase inhibitors.Formation of reactive metabolites and management of tyrosine kinase inhibitor-induced hepatotoxicity: a literature review.The contributions of Sidney D. Nelson to drug metabolism research.Synergistic disruption of ERα/HER2 crosstalk by endoxifen and lapatinib in breast cancer cells.Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of LapatinibDrug-drug interaction potential of marketed oncology drugs: in vitro assessment of time-dependent cytochrome P450 inhibition, reactive metabolite formation and drug-drug interaction prediction.Analysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial Agents.Lapatinib-associated mucocutaneous toxicities are clinical predictors of improved progression-free survival in patients with human epidermal growth factor receptor (HER2)-positive advanced breast cancer.Role of Cytochrome P450 Enzymes in the Metabolic Activation of Tyrosine Kinase Inhibitors
P2860
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P2860
Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.
@ast
Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.
@en
type
label
Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.
@ast
Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.
@en
prefLabel
Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.
@ast
Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.
@en
P2093
P2860
P356
P1476
Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.
@en
P2093
Chunsheng Zhao
Eric Chun Yong Chan
Hideo Takakusa
Kelsey L Hanson
Lee Sun New
Michelle D Wahlin
Sidney D Nelson
P2860
P304
P356
10.1124/DMD.110.037531
P577
2011-03-01T00:00:00Z