Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction.
about
Unfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion DiseasesRedox control of protein degradationCalcium binding promotes prion protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure.Role of prion protein aggregation in neurotoxicity.An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples.A computationally designed DNA aptamer template with specific binding to phosphatidylserine.Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cellsDifferent Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90-231 Neurotoxic Effects in Cerebellar Granule Neurons.A novel collection of snRNA-like promoters with tissue-specific transcription properties.Analysis of apoptosis methods recently used in Cancer Research and Cell Death & Disease publications.Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors.Localization of A11-reactive oligomeric species in prion diseases.C-terminal peptides modelling constitutive PrPC processing demonstrate ameliorated toxicity predisposition consequent to α-cleavage.Excitotoxicity through NMDA receptors mediates cerebellar granule neuron apoptosis induced by prion protein 90-231 fragment.Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death.
P2860
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P2860
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Human PrP90-231-induced cell d ...... tes and lysosomal dysfunction.
@ast
Human PrP90-231-induced cell d ...... tes and lysosomal dysfunction.
@en
type
label
Human PrP90-231-induced cell d ...... tes and lysosomal dysfunction.
@ast
Human PrP90-231-induced cell d ...... tes and lysosomal dysfunction.
@en
prefLabel
Human PrP90-231-induced cell d ...... tes and lysosomal dysfunction.
@ast
Human PrP90-231-induced cell d ...... tes and lysosomal dysfunction.
@en
P2860
P50
P356
P1476
Human PrP90-231-induced cell d ...... tes and lysosomal dysfunction.
@en
P2093
P2860
P2888
P356
10.1038/CDDIS.2011.21
P577
2011-03-31T00:00:00Z
P5875
P6179
1049354835