Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity - Wikidata - awgldk - TriplyDB

Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity

Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity

http://www.wikidata.org/entity/Q35008383

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Cellular imaging: a key phenotypic screening strategy for predictive toxicology A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) to Monitor Compound Effects on Cardiac Myocyte Signaling Pathways.In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model.Standardizing benchmark dose calculations to improve science-based decisions in human health assessments.Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II.Exposure to phthalates affects calcium handling and intercellular connectivity of human stem cell-derived cardiomyocytes High Throughput Measurement of Ca++ Dynamics in Human Stem Cell-Derived Cardiomyocytes by Kinetic Image Cytometery: A Cardiac Risk Assessment Characterization Using a Large Panel of Cardioactive and Inactive Compounds.Study of the union method of microelectrode array and AFM for the recording of electromechanical activities in living cardiomyocytes.Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes Functional Maturation of Induced Pluripotent Stem Cell Hepatocytes in Extracellular Matrix-A Comparative Analysis of Bioartificial Liver Microenvironments.Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform.Human stem cell-derived cardiomyocytes in cellular impedance assays: bringing cardiotoxicity screening to the front line.Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups.Programming microphysiological systems for children's health protection.Induced pluripotent stem cells: at the heart of cardiovascular precision medicine.Can Human Pluripotent Stem Cell-Derived Cardiomyocytes Advance Understanding of Muscular Dystrophies?From the Cover: High-Throughput Imaging of Cardiac Microtissues for the Assessment of Cardiac Contraction during Drug Discovery.Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales Hypertension Susceptibility Loci are Associated with Anthracycline-related Cardiotoxicity in Long-term Childhood Cancer Survivors.Stem cell derived in vivo-like human cardiac bodies in a microfluidic device for toxicity testing by beating frequency imaging.Enhanced characterization of contractility in cardiomyocytes during early drug safety assessment.High-Content Assay Multiplexing for Toxicity Screening in Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Hepatocytes Prospects and Frontiers of Stem Cell Toxicology A Pipeline for High-Throughput Concentration Response Modeling of Gene Expression for Toxicogenomics.Technological Advances in Cardiovascular Safety Assessment Decrease Preclinical Animal Use and Improve Clinical Relevance.An impedance-based cellular assay using human iPSC-derived cardiomyocytes to quantify modulators of cardiac contractility.Introduction of Exogenous HSV-TK Suicide Gene Increases Safety of Keratinocyte-Derived Induced Pluripotent Stem Cells by Providing Genetic "Emergency Exit" Switch.Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening.Development of In Vitro Drug-Induced Cardiotoxicity Assay by Using Three-Dimensional Cardiac Tissues Derived from Human Induced Pluripotent Stem Cells.Optical Method to Quantify Mechanical Contraction and Calcium Transients of Human Pluripotent Stem Cell-Derived Cardiomyocytes.Reflective lens-free imaging on high-density silicon microelectrode arrays for monitoring and evaluation of in vitro cardiac contractility.Disruption of neonatal cardiomyocyte physiology following exposure to bisphenol-a.Teratogen screening with human pluripotent stem cells An Ultrasensitive Calcium Reporter System via CRISPR-Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells

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P2860

Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity

http://www.wikidata.org/entity/Q35008383

description

2013 nî lūn-bûn

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2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2013 թվականի հոտեմբերին հրատարակված գիտական հոդված

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Assessment of beating paramete ...... o screening for cardiotoxicity

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Toxicology and Applied Pharmacology

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P2860

International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on terms and symbols in quantitative pharmacology

Cardiac excitation-contraction coupling

Predictive modeling of chemical hazard by integrating numerical descriptors of chemical structures and short-term toxicity assay data

Can the pharmaceutical industry reduce attrition rates?

pROC: an open-source package for R and S+ to analyze and compare ROC curves

ToxPi GUI: an interactive visualization tool for transparent integration of data from diverse sources of evidence.

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents.

Multiparameter in vitro assessment of compound effects on cardiomyocyte physiology using iPSC cells.

The point of transition on the dose-effect curve as a reference point in the evaluation of in vitro toxicity data.

QT alterations in psychopharmacology: proven candidates and suspects.

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Human Induced Pluripotent Stem Cells

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