Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2 - Wikidata - awgldk - TriplyDB

Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2

Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2

http://www.wikidata.org/entity/Q35010932

about

From UBE3A to Angelman syndrome: a substrate perspective Epigenetic regulation of UBE3A and roles in human neurodevelopmental disorders.Papillomavirus E6 oncoproteins.A homozygous missense mutation in HERC2 associated with global developmental delay and autism spectrum disorder.Functional and pathological relevance of HERC family proteins: a decade later.Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.Gene expression analysis of human induced pluripotent stem cell-derived neurons carrying copy number variants of chromosome 15q11-q13.1.Role of ubiquitin and the HPV E6 oncoprotein in E6AP-mediated ubiquitination Complete loss of function of the ubiquitin ligase HERC2 causes a severe neurodevelopmental phenotype.Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes.Comprehensive analysis of host cellular interactions with human papillomavirus E6 proteins identifies new E6 binding partners and reflects viral diversity Proteomic approaches to the study of papillomavirus-host interactions.Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc The role of ubiquitin and ubiquitin-like modification systems in papillomavirus biology.Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase.The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization A genomic survey of HECT ubiquitin ligases in eukaryotes reveals independent expansions of the HECT system in several lineages.The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination.Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome.Targeting HECT-type E3 ligases - insights from catalysis, regulation and inhibitors.Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons.Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes.Neurodevelopmental disease: A molecular tightrope.Insights into the ubiquitin-proteasome system of human embryonic stem cells.Structural dynamics of the E6AP/UBE3A-E6-p53 enzyme-substrate complex

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Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2

http://www.wikidata.org/entity/Q35010932

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2

@ast

Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2

@en

type

label

Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2

@ast

Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2

@en

prefLabel

Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2

@ast

Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2

@en

P1433

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P356

JBC.M110.205211

P1433

Journal of Biological Chemistry

P1476

Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2

@en

P2093

Andreas Marquardt

http://www.w3.org/2001/XMLSchema#string

Konstantin Matentzoglu

http://www.w3.org/2001/XMLSchema#string

Sandra Glockzin

http://www.w3.org/2001/XMLSchema#string

Simone Kühnle

http://www.w3.org/2001/XMLSchema#string

Ulrike Kogel

http://www.w3.org/2001/XMLSchema#string

P2860

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase

UBE3A/E6-AP mutations cause Angelman syndrome

Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5

Involvement of the DNA repair protein hHR23 in p53 degradation

Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination

Angelman syndrome: a review of the clinical and genetic aspects

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

RING domain E3 ubiquitin ligases

Molecular characterization of radiation- and chemically induced mutations associated with neuromuscular tremors, runting, juvenile lethality, and sperm defects in jdf2 mice

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10.1074/JBC.M110.205211

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22

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286

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Aaron Ciechanover

Martin Scheffner

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2011-04-14T00:00:00Z

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3103319

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