Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
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miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in miceMicroRNAs in platelet production and activationEmerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer developmentClinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasmsmiR-145-mediated suppression of cell growth, invasion and metastasisUnraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS PhenotypeImmune Mechanisms in Myelodysplastic SyndromeGenomic landscape of megakaryopoiesis and platelet function defectsThe Emerging Role of miRNAs in HTLV-1 Infection and ATLL PathogenesisMicroRNAs and the resolution phase of inflammation in macrophagesEngineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they?MicroRNA-146a: A Dominant, Negative Regulator of the Innate Immune ResponseRevisiting the case for genetically engineered mouse models in human myelodysplastic syndrome researchIRAK signalling in cancerRole of microRNA-146a in normal and malignant hematopoietic stem cell functionDeconstructing innate immune signaling in myelodysplastic syndromesTumor suppressor microRNAs: a novel non-coding alliance against cancerMicroRNAs: new regulators of Toll-like receptor signalling pathwaysDeregulation of innate immune and inflammatory signaling in myelodysplastic syndromesGuarding the 'translation apparatus': defective ribosome biogenesis and the p53 signaling pathwaymiRNA dysregulation in cancer: towards a mechanistic understandingPP2A: The Achilles Heal in MDS with 5q DeletionThe Role of Toll-Like Receptors in Hematopoietic MalignanciesKnockdown of Hspa9, a del(5q31.2) gene, results in a decrease in hematopoietic progenitors in miceNPM1 deletion is associated with gross chromosomal rearrangements in leukemiaFunctional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity.miR-146a enhances the oncogenicity of oral carcinoma by concomitant targeting of the IRAK1, TRAF6 and NUMB genes.Evaluation of TRAF6 in a large multiancestral lupus cohortAdvances in megakaryocytopoiesis and thrombopoiesis: from bench to bedside.[Myelodysplastic syndromes].Myelodysplastic syndromes: Contemporary review and how we treat.Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid LeukemiaToll-like receptor alterations in myelodysplastic syndromeSRF is required for neutrophil migration in response to inflammation.Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemiaEmerging roles for natural microRNA sponges.Ribosomopathies: human disorders of ribosome dysfunction.Premalignant PTEN-deficient thymocytes activate microRNAs miR-146a and miR-146b as a cellular defense against malignant transformation.
P2860
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P2860
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
@ast
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
@en
type
label
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
@ast
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
@en
prefLabel
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
@ast
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
@en
P2093
P356
P1433
P1476
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
@en
P2093
Aly Karsan
Andrew Muranyi
Bob Argiropoulos
Daniel T Starczynowski
Donna Hogge
Florian Kuchenbauer
Marco Marra
Martin Hirst
Rena Buckstein
Richard A Wells
P2888
P356
10.1038/NM.2054
P407
P577
2009-11-08T00:00:00Z
P5875
P6179
1021915407