Protective capacity of memory CD8+ T cells is dictated by antigen exposure history and nature of the infection
about
Hidden memories: frontline memory T cells and early pathogen interceptionInfluenza and Memory T Cells: How to Awake the ForceIL-15 regulates memory CD8+ T cell O-glycan synthesis and affects traffickingA Role of Influenza Virus Exposure History in Determining Pandemic Susceptibility and CD8+ T Cell ResponsesDynamic functional modulation of CD4+ T cell recall responses is dependent on the inflammatory environment of the secondary stimulus.An MHC class Ib-restricted CD8+ T cell response to lymphocytic choriomeningitis virus.Regulation of T Cell Trafficking by Enzymatic Synthesis of O-Glycans.Increased T-bet is associated with senescence of influenza virus-specific CD8 T cells in aged humans.Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life.Augmented replicative capacity of the boosting antigen improves the protective efficacy of heterologous prime-boost vaccine regimens.The longevity of memory CD8 T cell responses after repetitive antigen stimulationsTranscriptional control of effector and memory CD8+ T cell differentiation.Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infectionRedefining chronic toxoplasmosis--a T cell exhaustion perspective.The initial draining lymph node primes the bulk of the CD8 T cell response and influences memory T cell trafficking after a systemic viral infectionKinetic and phenotypic analysis of CD8+ T cell responses after priming with alphavirus replicons and homologous or heterologous booster immunizationsCooperativity between CD8+ T cells, non-neutralizing antibodies, and alveolar macrophages is important for heterosubtypic influenza virus immunity.Antigen experience shapes phenotype and function of memory Th1 cellsTargeting of non-dominant antigens as a vaccine strategy to broaden T-cell responses during chronic viral infection.Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics.Molecular mechanisms of CD8(+) T cell trafficking and localizationPolymicrobial Sepsis Increases Susceptibility to Chronic Viral Infection and Exacerbates CD8+ T Cell Exhaustion.Phenotypic and Functional Alterations in Circulating Memory CD8 T Cells with Time after Primary Infection.An Excess of the Proinflammatory Cytokines IFN-γ and IL-12 Impairs the Development of the Memory CD8+ T Cell Response to Chlamydia trachomatis.Inflammatory IL-15 is required for optimal memory T cell responses.Antigen-dependent and -independent contributions to primary memory CD8 T cell activation and protection following infectionUse it or lose it: establishment and persistence of T cell memory.T cell vaccinology: exploring the known unknowns.C-Myc regulation by costimulatory signals modulates the generation of CD8+ memory T cells during viral infection.Pathogen-specific inflammatory milieux tune the antigen sensitivity of CD8(+) T cells by enhancing T cell receptor signalingSustained and incomplete recovery of naive CD8+ T cell precursors after sepsis contributes to impaired CD8+ T cell responses to infectionQualitative and quantitative analysis of adenovirus type 5 vector-induced memory CD8 T cells: not as bad as their reputation.Discriminating Protective from Nonprotective Plasmodium-Specific CD8+ T Cell ResponsesEffector-like CD8⁺ T cells in the memory population mediate potent protective immunity.Virtual memory CD8 T cells display unique functional propertiesInhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.Aging promotes acquisition of naive-like CD8+ memory T cell traits and enhanced functionalities.Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virusEarly life vaccination: Generation of adult-quality memory CD8+ T cells in infant mice using non-replicating adenoviral vectors.Antigen Exposure History Defines CD8 T Cell Dynamics and Protection during Localized Pulmonary Infections.
P2860
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P2860
Protective capacity of memory CD8+ T cells is dictated by antigen exposure history and nature of the infection
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Protective capacity of memory ...... ry and nature of the infection
@ast
Protective capacity of memory ...... ry and nature of the infection
@en
type
label
Protective capacity of memory ...... ry and nature of the infection
@ast
Protective capacity of memory ...... ry and nature of the infection
@en
prefLabel
Protective capacity of memory ...... ry and nature of the infection
@ast
Protective capacity of memory ...... ry and nature of the infection
@en
P2860
P1433
P1476
Protective capacity of memory ...... ry and nature of the infection
@en
P2093
Jeffrey C Nolz
P2860
P304
P356
10.1016/J.IMMUNI.2011.03.020
P407
P50
P577
2011-05-05T00:00:00Z