about
Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca2+ signaling in B cellsGerminal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activationSignalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright.Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activationAntibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized miceToll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responsesRegulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombinationProtein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosisGlobal transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cellsNF-kB inhibitor blocks B cell development at two checkpointsRole of the tumor microenvironment in mature B-cell lymphoid malignanciesDifferential impact of Toll-like receptor signaling on distinct B cell subpopulationsMolecular pathways: targeting phosphoinositide 3-kinase p110-delta in chronic lymphocytic leukemiaProtein kinase inhibitors against malignant lymphomaTargeting neoplastic B cells and harnessing microenvironment: the "double face" of ibrutinib and idelalisibPreclinical validation of interleukin 6 as a therapeutic target in multiple myelomaSecond-generation inhibitors of Bruton tyrosine kinaseHeterogeneity of B Cell Functions in Stroke-Related Risk, Prevention, Injury, and RepairRedirection of B cell responsiveness by transforming growth factor beta receptorCD22: an inhibitory enigmaPrimary mediastinal B-cell lymphoma: treatment and therapeutic targetsSurvey of activated FLT3 signaling in leukemiaTyrosine phosphorylation within the intrinsically disordered cytosolic domains of the B-cell receptor: an NMR-based structural analysisA gammaherpesvirus Bcl-2 ortholog blocks B cell receptor-mediated apoptosis and promotes the survival of developing B cells in vivoFunctional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survivalThe adaptor protein Shc plays a key role during early B cell developmentSyk-dependent actin dynamics regulate endocytic trafficking and processing of antigens internalized through the B-cell receptorB cell antigen receptor signaling and internalization are mutually exclusive events.Gene expression profile of bladder tissue of patients with ulcerative interstitial cystitisA Myc-regulated transcriptional network controls B-cell fate in response to BCR triggering.AUF1 is involved in splenic follicular B cell maintenanceAugmented B lymphocyte response to antigen in the absence of antigen-induced B lymphocyte signaling in an IgG-transgenic mouse lineA novel subset of memory B cells is enriched in autoreactivity and correlates with adverse outcomes in SLEAnomalous constitutive Src kinase activity promotes B lymphoma survival and growth.Targeting CD22 with the monoclonal antibody epratuzumab modulates human B-cell maturation and cytokine production in response to Toll-like receptor 7 (TLR7) and B-cell receptor (BCR) signalingChronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.Defining the antigen receptor-dependent regulatory network that induces arrest of cycling immature B-lymphocytes.Pediatric posttransplant relapsed/refractory B-precursor acute lymphoblastic leukemia shows durable remission by therapy with the T-cell engaging bispecific antibody blinatumomab.Epstein-Barr virus (EBV) latent membrane protein 2A regulates B-cell receptor-induced apoptosis and EBV reactivation through tyrosine phosphorylation.Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) has significant activity in patients with relapsed/refractory B-cell malignancies.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Regulation of B-cell fate by antigen-receptor signals.
@ast
Regulation of B-cell fate by antigen-receptor signals.
@en
type
label
Regulation of B-cell fate by antigen-receptor signals.
@ast
Regulation of B-cell fate by antigen-receptor signals.
@en
prefLabel
Regulation of B-cell fate by antigen-receptor signals.
@ast
Regulation of B-cell fate by antigen-receptor signals.
@en
P356
P1476
Regulation of B-cell fate by antigen-receptor signals.
@en
P2093
Hiroaki Niiro
P2888
P304
P356
10.1038/NRI955
P577
2002-12-01T00:00:00Z
P6179
1038577520