Human cystatin C. role of the N-terminal segment in the inhibition of human cysteine proteinases and in its inactivation by leucocyte elastase.
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Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysisIdentification, cloning, and characterization of cystatin M, a novel cysteine proteinase inhibitor, down-regulated in breast cancerStructural basis for the biological specificity of cystatin C. Identification of leucine 9 in the N-terminal binding region as a selectivity-conferring residue in the inhibition of mammalian cysteine peptidasesRole of the single cysteine residue, Cys 3, of human and bovine cystatin B (stefin B) in the inhibition of cysteine proteinasesCysteine proteinase inhibitor cystatin C in squamous cell carcinoma of the head and neck: relation to prognosisIncreased cystatin C expression in the pre-eclamptic placentaThe role of cystatin C in cerebral amyloid angiopathy and stroke: cell biology and animal modelsNormal sexual development and fertility in testatin knockout mice.Truncated cystatin C in cerebrospiral fluid: Technical [corrected] artefact or biological process?Cleavage of cystatin C in the cerebrospinal fluid of patients with multiple sclerosis.Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines.An overview of proteinase inhibitors.Proteomics of dense core secretory vesicles reveal distinct protein categories for secretion of neuroeffectors for cell-cell communication.Biochemistry and clinical role of human cystatin C.Crystal structure of human cystatin D, a cysteine peptidase inhibitor with restricted inhibition profile.Inhibitory properties of cystatin F and its localization in U937 promonocyte cells.Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease.Imaging proteolysis by living human breast cancer cells.Salivary (SD-type) cystatins: over one billion years in the making--but to what purpose?Evidence of Alternative Cystatin C Signal Sequence Cleavage Which Is Influenced by the A25T Polymorphism.The N-terminal region of cystatin A (stefin A) binds to papain subsequent to the two hairpin loops of the inhibitor. Demonstration of two-step binding by rapid-kinetic studies of cystatin A labeled at the N-terminus with a fluorescent reporter groupUnveiling New Molecular Factors Useful for Detection of Pelvic Inflammatory Disease due to Chlamydia trachomatis Infection.Expression, purification, and characterization of human cystatin C monomers and oligomers.The association of plasma cystatin C proteoforms with diabetic chronic kidney diseaseCystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activityModification of cystatin C activity by bacterial proteinases and neutrophil elastase in periodontitis.Cystatin C properties crucial for uptake and inhibition of intracellular target enzymes.Characterization of a cysteine proteinase inhibitor induced during neuronal cell differentiation.Cystatins in health and disease.Expression of cysteine protease inhibitors in human gliomas and meningiomas.Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin.Cystatin C and cathepsin B in human colon carcinoma: expression by cell lines and matrix degradation.Human sputum cathepsin B degrades proteoglycan, is inhibited by alpha 2-macroglobulin and is modulated by neutrophil elastase cleavage of cathepsin B precursor and cystatin C.Differential changes in the association and dissociation rate constants for binding of cystatins to target proteinases occurring on N-terminal truncation of the inhibitors indicate that the interaction mechanism varies with different enzymes.Hereditary cystatin C amyloid angiopathy: monitoring the presence of the Leu-68-->Gln cystatin C variant in cerebrospinal fluids and monocyte cultures by MS.Local pH-dependent conformational changes leading to proteolytic susceptibility of cystatin C.Purification and characterization of a new cystatin inhibitor from Taiwan cobra (Naja naja atra) venom.Characterization by spectroscopic, kinetic and equilibrium methods of the interaction between recombinant human cystatin A (stefin A) and cysteine proteinases.Probing the functional role of the N-terminal region of cystatins by equilibrium and kinetic studies of the binding of Gly-11 variants of recombinant human cystatin C to target proteinases.Characterization by rapid-kinetic and equilibrium methods of the interaction between N-terminally truncated forms of chicken cystatin and the cysteine proteinases papain and actinidin.
P2860
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P2860
Human cystatin C. role of the N-terminal segment in the inhibition of human cysteine proteinases and in its inactivation by leucocyte elastase.
description
1991 nî lūn-bûn
@nan
1991 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Human cystatin C. role of the ...... ivation by leucocyte elastase.
@ast
Human cystatin C. role of the ...... ivation by leucocyte elastase.
@en
type
label
Human cystatin C. role of the ...... ivation by leucocyte elastase.
@ast
Human cystatin C. role of the ...... ivation by leucocyte elastase.
@en
prefLabel
Human cystatin C. role of the ...... ivation by leucocyte elastase.
@ast
Human cystatin C. role of the ...... ivation by leucocyte elastase.
@en
P2093
P2860
P356
P1433
P1476
Human cystatin C. role of the ...... ivation by leucocyte elastase.
@en
P2093
P2860
P304
P356
10.1042/BJ2730621
P407
P478
273 ( Pt 3)
P577
1991-02-01T00:00:00Z