RNA polymerase III drives alternative splicing of the potassium channel-interacting protein contributing to brain complexity and neurodegeneration
about
Absence of neurological abnormalities in mice homozygous for the Polr3a G672E hypomyelinating leukodystrophy mutationA greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset.Different KChIPs compete for heteromultimeric assembly with pore-forming Kv4 subunitsNovel classes of non-coding RNAs and cancerThe Murine PSE/TATA-dependent transcriptome: evidence of functional homologies with its human counterpart.A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced coughDivergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples.Auxiliary KChIP4a suppresses A-type K+ current through endoplasmic reticulum (ER) retention and promoting closed-state inactivation of Kv4 channelsGenetic susceptibility for Alzheimer disease neuritic plaque pathology.Novel ncRNAs transcribed by Pol III and elucidation of their functional relevance by biophysical approaches.The inhibition of 45A ncRNA expression reduces tumor formation, affecting tumor nodules compactness and metastatic potential in neuroblastoma cells.Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling.A novel collection of snRNA-like promoters with tissue-specific transcription properties.Down-regulation of 21A Alu RNA as a tool to boost proliferation maintaining the tissue regeneration potential of progenitor cells.Noncoding RNA to blame for bad editing.Complexity and Selectivity of γ-Secretase Cleavage on Multiple Substrates: Consequences in Alzheimer's Disease and Cancer.
P2860
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P2860
RNA polymerase III drives alternative splicing of the potassium channel-interacting protein contributing to brain complexity and neurodegeneration
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
RNA polymerase III drives alte ...... mplexity and neurodegeneration
@ast
RNA polymerase III drives alte ...... mplexity and neurodegeneration
@en
type
label
RNA polymerase III drives alte ...... mplexity and neurodegeneration
@ast
RNA polymerase III drives alte ...... mplexity and neurodegeneration
@en
prefLabel
RNA polymerase III drives alte ...... mplexity and neurodegeneration
@ast
RNA polymerase III drives alte ...... mplexity and neurodegeneration
@en
P2093
P2860
P50
P356
P1476
RNA polymerase III drives alte ...... mplexity and neurodegeneration
@en
P2093
Elena Gatta
Gloria Fiorino
Irene Vassallo
Manuele Castelnuovo
Massimo Tabaton
Mauro Robello
Ranieri Cancedda
Roberta Borghi
Sara Massone
P2860
P304
P356
10.1083/JCB.201011053
P407
P577
2011-05-01T00:00:00Z