Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
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Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biologyRecent progress in genetic and epigenetic research on type 2 diabetesGenetics of Type 2 Diabetes in African AmericansDiscovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density ImputationHuman genetics as a model for target validation: finding new therapies for diabetes.Genetic association of long-chain acyl-CoA synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosisTranscript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors.Genome-wide association study for feed efficiency and growth traits in U.S. beef cattleFamily-based approaches: design, imputation, analysis, and beyond.Genome-wide association studies and contribution to cardiovascular physiologyA Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.Recent advances in understanding the genetic architecture of type 2 diabetesFunctional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression.Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection.Multiple susceptibility loci at chromosome 11q23.3 are associated with plasma triglyceride in East Asians.On Sample Size and Power Calculation for Variant Set-Based Association Tests.On Efficient and Accurate Calculation of Significance P-Values for Sequence Kernel Association Testing of Variant Set.General Framework for Meta-Analysis of Haplotype Association Tests.Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.Vejle Diabetes Biobank - a resource for studies of the etiologies of diabetes and its comorbidities.Genetics of diabetic nephropathy: a long road of discovery.Prioritising Causal Genes at Type 2 Diabetes Risk Loci.Meta-analyses of the association of G6PC2 allele variants with elevated fasting glucose and type 2 diabetes.Common and rare forms of diabetes mellitus: towards a continuum of diabetes subtypes.Diabetes in Population Isolates: Lessons from Greenland.A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.Effects of G6pc2 deletion on body weight and cholesterol in mice.The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases.Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population.Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.Power Analysis for Genetic Association Test (PAGEANT) provides insights to challenges for rare variant association studies.DNA methylation profiles in sibling pairs discordant for intrauterine exposure to maternal gestational diabetes.Exome-chip association analysis reveals an Asian-specific missense variant in PAX4 associated with type 2 diabetes in Chinese individuals.Genetic aetiology of glycaemic traits: approaches and insights.Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS).Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey.An Exome-wide Association Study for Type 2 Diabetes–Attributed End-Stage Kidney Disease in African Americans.The Hunt for Low-Frequency Alleles Predisposing to Type 2 Diabetes and Related Cardiovascular Risk FactorsDeciphering the Emerging Complexities of Molecular Mechanisms at GWAS Loci
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P2860
Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
name
Identification and functional ...... ipt at the G6PC2-ABCB11 locus.
@ast
Identification and functional ...... ipt at the G6PC2-ABCB11 locus.
@en
type
label
Identification and functional ...... ipt at the G6PC2-ABCB11 locus.
@ast
Identification and functional ...... ipt at the G6PC2-ABCB11 locus.
@en
altLabel
Identification and functional ...... ript at the G6PC2-ABCB11 locus
@en
prefLabel
Identification and functional ...... ipt at the G6PC2-ABCB11 locus.
@ast
Identification and functional ...... ipt at the G6PC2-ABCB11 locus.
@en
P2093
P2860
P50
P1433
P1476
Identification and functional ...... ipt at the G6PC2-ABCB11 locus.
@en
P2093
Alex S F Doney
Alisa Manning
Andrew D Morris
Andrew P Morris
Christine Blancher
Christopher J Groves
Claes Ladenvall
Colin N A Palmer
Craig L Hanis
Cramer Christensen
P2860
P304
P356
10.1371/JOURNAL.PGEN.1004876
P407
P50
P577
2015-01-27T00:00:00Z