Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.
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Clear cell carcinoma of the ovary: molecular insights and future therapeutic perspectivesPotential targets for ovarian clear cell carcinoma: a review of updates and future perspectivesMammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomicsSingle and Multiple Gene Manipulations in Mouse Models of Human CancerModels of endometriosis and their utility in studying progression to ovarian clear cell carcinomaGenetic alterations in hepatocellular carcinoma: An updateGenome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF ComplexesDeletion of Arid1a in Reproductive Tract Mesenchymal Cells Reduces Fertility in Female Mice.Involvement of Chromatin Remodeling Genes and the Rho GTPases RhoB and CDC42 in Ovarian Clear Cell Carcinoma.Network-based survival-associated module biomarker and its crosstalk with cell death genes in ovarian cancer.Hepatocyte-Specific Arid1a Deficiency Initiates Mouse Steatohepatitis and Hepatocellular Carcinoma.Modification of the Tumor Microenvironment in KRAS or c-MYC-Induced Ovarian Cancer-Associated PeritonitisGlobal gene expression profiling of a mouse model of ovarian clear cell carcinoma caused by ARID1A and PIK3CA mutations implicates a role for inflammatory cytokine signaling.Potential therapeutic targets in ARID1A-mutated cancersArid1a inactivation in an Apc- and Pten-defective mouse ovarian cancer model enhances epithelial differentiation and prolongs survival.The SWI/SNF BAF-A complex is essential for neural crest developmentClinicopathologic Significance of HNF-1β, AIRD1A, and PIK3CA Expression in Ovarian Clear Cell Carcinoma: A Tissue Microarray Study of 130 CasesEpigenetic synthetic lethality in ovarian clear cell carcinoma: EZH2 and ARID1A mutationsInactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells.Effective use of PI3K inhibitor BKM120 and PARP inhibitor Olaparib to treat PIK3CA mutant ovarian cancer.Chromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1.Characterization of ovarian clear cell carcinoma using target drug-based molecular biomarkers: implications for personalized cancer therapy.The Dualistic Model of Ovarian Carcinogenesis: Revisited, Revised, and Expanded.Antitumor effects of interleukin-6 (IL-6)/interleukin-6 receptor (IL-6R) signaling pathway inhibition in clear cell carcinoma of the ovary.The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer.(Partial) Loss of BAF250a (ARID1A) in rectovaginal deep-infiltrating endometriosis, endometriomas and involved pelvic sentinel lymph nodes.Endometrial receptivity in the eutopic endometrium of women with endometriosis: it is affected, and let me show you why.Preclinical Models of Ovarian Cancer: Pathogenesis, Problems, and Implications for Prevention.Suppression of the SWI/SNF Component Arid1a Promotes Mammalian Regeneration.TGFβ Controls Ovarian Cancer Cell ProliferationArid1a controls tissue regeneration.The Chromatin Remodeling Component Arid1a Is a Suppressor of Spontaneous Mammary Tumors in Mice.Response to sunitinib (Sutent) in chemotherapy refractory clear cell ovarian cancer.Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.Impact of oviductal versus ovarian epithelial cell of origin on ovarian endometrioid carcinoma phenotype in the mouse.Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits.Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing.Ovarian Cancers: Genetic Abnormalities, Tumor Heterogeneity and Progression, Clonal Evolution and Cancer Stem Cells.Targeting STAT3 by HO3867 induces apoptosis in ovarian clear cell carcinoma.ARID1A-mutated ovarian cancers depend on HDAC6 activity.
P2860
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P2860
Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.
description
2015 nî lūn-bûn
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Coexistent ARID1A-PIK3CA mutat ...... lammatory cytokine signalling.
@ast
Coexistent ARID1A-PIK3CA mutat ...... lammatory cytokine signalling.
@en
type
label
Coexistent ARID1A-PIK3CA mutat ...... lammatory cytokine signalling.
@ast
Coexistent ARID1A-PIK3CA mutat ...... lammatory cytokine signalling.
@en
prefLabel
Coexistent ARID1A-PIK3CA mutat ...... lammatory cytokine signalling.
@ast
Coexistent ARID1A-PIK3CA mutat ...... lammatory cytokine signalling.
@en
P2093
P2860
P50
P356
P1476
Coexistent ARID1A-PIK3CA mutat ...... lammatory cytokine signalling.
@en
P2093
Daniel Serber
David B Darr
Fernando Pardo-Manuel de Villena
Jeffrey S Damrauer
Jessie Xiong
Joshua Starmer
Matthew D Wilkerson
Ronald L Chandler
Terry Magnuson
P2860
P2888
P356
10.1038/NCOMMS7118
P407
P577
2015-01-27T00:00:00Z