Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations. - Wikidata - awgldk - TriplyDB

Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations.

Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations.

http://www.wikidata.org/entity/Q35021606

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The Use of Stem Cells to Model Amyotrophic Lateral Sclerosis and Frontotemporal Dementia: From Basic Research to Regenerative Medicine Frontotemporal Lobar Degeneration and MicroRNAs Induced Pluripotent Stem Cells as a Novel Tool in Psychiatric Research ALS Patient Stem Cells for Unveiling Disease Signatures of Motoneuron Susceptibility: Perspectives on the Deadly Mitochondria, ER Stress and Calcium Triad Modeling ALS and FTD with iPSC-derived neurons A perspective on stem cell modeling of amyotrophic lateral sclerosis Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.The emerging roles of microRNAs in the pathogenesis of frontotemporal dementia-amyotrophic lateral sclerosis (FTD-ALS) spectrum disorders GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.Reversible behavioral phenotypes in a conditional mouse model of TDP-43 proteinopathies Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS.Progranulin and Its Related MicroRNAs after Status Epilepticus: Possible Mechanisms of Neuroprotection.Expression of microRNAs in human post-mortem amyotrophic lateral sclerosis spinal cords provides insight into disease mechanisms M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b.Cytoplasmic Relocalization of TAR DNA-Binding Protein 43 Is Not Sufficient to Reproduce Cellular Pathologies Associated with ALS In vitro.The role of miRNA in motor neuron disease.Targeting TDP-43 in neurodegenerative diseases.Human-induced pluripotent stem cells: potential for neurodegenerative diseases.Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins.ALS and FTD: an epigenetic perspective.Review: Induced pluripotent stem cell models of frontotemporal dementia.Validation of microRNAs in Cerebrospinal Fluid as Biomarkers for Different Forms of Dementia in a Multicenter Study.Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux.Decoding ALS: from genes to mechanism.ALS/FTLD: experimental models and reality.Constitutional Epi/Genetic Conditions: Genetic, Epigenetic, and Environmental Factors.Serum microRNAs in patients with genetic amyotrophic lateral sclerosis and pre-manifest mutation carriers.RNA Misprocessing in C9orf72-Linked Neurodegeneration.4-Aminopyridine Induced Activity Rescues Hypoexcitable Motor Neurons from Amyotrophic Lateral Sclerosis Patient-Derived Induced Pluripotent Stem Cells.TDP-43 regulates cancer-associated microRNAs.TDP-43 misexpression causes defects in dendritic growth.Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia.Current Advances and Limitations in Modeling ALS/FTD in a Dish Using Induced Pluripotent Stem Cells.TDP43 and RNA instability in amyotrophic lateral sclerosis.Epigenetic Mechanisms of Gene Regulation in Amyotrophic Lateral Sclerosis.Differential Expression of Several miRNAs and the Host Genes AATK and DNM2 in Leukocytes of Sporadic ALS Patients.Differential expression of microRNAs and other small RNAs in muscle tissue of patients with ALS and healthy age-matched controls.Linking hnRNP Function to ALS and FTD Pathology.2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling.

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Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations.

http://www.wikidata.org/entity/Q35021606

description

2013 nî lūn-bûn

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2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2013 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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Downregulation of microRNA-9 i ...... atients with TDP-43 mutations.

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Downregulation of microRNA-9 i ...... atients with TDP-43 mutations.

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Downregulation of microRNA-9 i ...... atients with TDP-43 mutations.

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Downregulation of microRNA-9 i ...... atients with TDP-43 mutations.

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Downregulation of microRNA-9 i ...... atients with TDP-43 mutations.

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Downregulation of microRNA-9 i ...... patients with TDP-43 mutations

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Agnes L Nishimura

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Anna M Karydas

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Bei Wu

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Bruce L Miller

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Danqiong Sun

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Fen-Biao Gao

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Jamie C Fong

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Lingtao Peng

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Maria C Tartaglia

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Melissa J Moore

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P2860

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

The Microprocessor complex mediates the genesis of microRNAs

ESCRT-III subunits Snf7-1 and Snf7-2 differentially regulate transmembrane cargos in hESC-derived human neurons

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors

Exome sequencing reveals VCP mutations as a cause of familial ALS

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

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amyotrophic lateral sclerosis

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