Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness - Wikidata - awgldk - TriplyDB

Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness

Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness

http://www.wikidata.org/entity/Q35022183

about

TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cells JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships Effect of Cigarette Smoking on Epithelial to Mesenchymal Transition (EMT) in Lung Cancer Mitogen-activated protein kinase signaling pathway and invasion and metastasis of gastric cancer The emerging role of Twist proteins in hematopoietic cells and hematological malignancies Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms Molecular mechanisms of epithelial-mesenchymal transition AKT-ions with a TWIST between EMT and MET Tackling Cancer Stem Cells via Inhibition of EMT Transcription Factors Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition Twist: a molecular target in cancer therapeutics P130cas is required for TGF-β1-mediated epithelial-mesenchymal transition in lung cancer NID1, a new regulator of EMT required for metastasis and chemoresistance of ovarian cancer cells Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells.De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells.Multilayer control of the EMT master regulators.MAPK11 in breast cancer cells enhances osteoclastogenesis and bone resorption.Sox2 suppresses the invasiveness of breast cancer cells via a mechanism that is dependent on Twist1 and the status of Sox2 transcription activity.Structure-function studies of the bHLH phosphorylation domain of TWIST1 in prostate cancer cells Tamoxifen inhibits ER-negative breast cancer cell invasion and metastasis by accelerating Twist1 degradation.KITENIN promotes glioma invasiveness and progression, associated with the induction of EMT and stemness markers.Over-Expressed Twist Associates with Markers of Epithelial Mesenchymal Transition and Predicts Poor Prognosis in Breast Cancers via ERK and Akt Activation.Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer Cells The function of steroid receptor coactivator-1 in normal tissues and cancer TWIST represses estrogen receptor-alpha expression by recruiting the NuRD protein complex in breast cancer cells.PRMT1 Is a Novel Regulator of Epithelial-Mesenchymal-Transition in Non-small Cell Lung Cancer.The Small C-terminal Domain Phosphatase 1 Inhibits Cancer Cell Migration and Invasion by Dephosphorylating Ser(P)68-Twist1 to Accelerate Twist1 Protein Degradation EGFR Signal-Network Reconstruction Demonstrates Metabolic Crosstalk in EMT.MACC-1 Promotes Endothelium-Dependent Angiogenesis in Gastric Cancer by Activating TWIST1/VEGF-A Signal Pathway.Negative Regulatory Role of TWIST1 on SNAIL Gene Expression.Regulation of the protein stability of EMT transcription factors Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition.Twist1 regulates keratinocyte proliferation and skin tumor promotion.DLX4 upregulates TWIST and enhances tumor migration, invasion and metastasis The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial-mesenchymal transition in a sumoylation-regulated manner.Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasis Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species.Epithelial-mesenchymal transition in breast cancer progression and metastasis.Preventing p38 MAPK-mediated MafA degradation ameliorates β-cell dysfunction under oxidative stress.

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Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness

http://www.wikidata.org/entity/Q35022183

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2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Phosphorylation of serine 68 o ...... reast cancer cell invasiveness

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Phosphorylation of serine 68 o ...... reast cancer cell invasiveness

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type

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Phosphorylation of serine 68 o ...... reast cancer cell invasiveness

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Phosphorylation of serine 68 o ...... reast cancer cell invasiveness

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prefLabel

Phosphorylation of serine 68 o ...... reast cancer cell invasiveness

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Phosphorylation of serine 68 o ...... reast cancer cell invasiveness

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0008-5472.CAN-10-2914

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Cancer Research

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Phosphorylation of serine 68 o ...... reast cancer cell invasiveness

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Jian Zhou

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Jianming Xu

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Jun Hong

http://www.w3.org/2001/XMLSchema#string

Jun Qin

http://www.w3.org/2001/XMLSchema#string

Junjiang Fu

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Lan Liao

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Li Wang

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Tao He

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P2860

An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ

Saethre-Chotzen mutations cause TWIST protein degradation or impaired nuclear location

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence

The epithelial-mesenchymal transition generates cells with properties of stem cells

Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

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3980-3990

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10.1158/0008-5472.CAN-10-2914

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11

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2011-04-18T00:00:00Z

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51060160

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21502402

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phosphorylation

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3107354

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