Mutation of dileucine-like motifs in the human immunodeficiency virus type 1 capsid disrupts virus assembly, gag-gag interactions, gag-membrane binding, and virion maturation
about
HIV type 1 Gag as a target for antiviral therapyTissue-spanning redox gradient-dependent assembly of native human papillomavirus type 16 virionsPapillomavirus Infectious Pathways: A Comparison of SystemsNucleocapsid promotes localization of HIV-1 gag to uropods that participate in virological synapses between T cellsReal-time visualization of HIV-1 GAG trafficking in infected macrophagesPoint Mutations in the HIV-1 Matrix Protein Turn Off the Myristyl SwitchDomain-swapped dimerization of the HIV-1 capsid C-terminal domainMature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamicsEfficient production of HIV-1 virus-like particles from a mammalian expression vector requires the N-terminal capsid domainSTRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.A cell-penetrating helical peptide as a potential HIV-1 inhibitor.How HIV-1 Gag assembles in cells: Putting together pieces of the puzzle.Defects in cellular sorting and retroviral assembly induced by GGA overexpressionRoles for human papillomavirus type 16 l1 cysteine residues 161, 229, and 379 in genome encapsidation and capsid stabilityVirtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid.Myristate exposure in the human immunodeficiency virus type 1 matrix protein is modulated by pH.Quantitative fluorescence resonance energy transfer microscopy analysis of the human immunodeficiency virus type 1 Gag-Gag interaction: relative contributions of the CA and NC domains and membrane binding.Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domainTargeting the HIV entry, assembly and release pathways for anti-HIV gene therapy.In vitro resistance to the human immunodeficiency virus type 1 maturation inhibitor PA-457 (Bevirimat).Evidence of a role for soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) machinery in HIV-1 assembly and release.HIV ENV glycoprotein-mediated bystander apoptosis depends on expression of the CCR5 co-receptor at the cell surface and ENV fusogenic activityGag induces the coalescence of clustered lipid rafts and tetraspanin-enriched microdomains at HIV-1 assembly sites on the plasma membrane.Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly.GGA and Arf proteins modulate retrovirus assembly and releaseHIV-1 Capsid Inhibitors as Antiretroviral AgentsFunctional replacement of a retroviral late domain by ubiquitin fusion.Mutations in the thumb allow human immunodeficiency virus type 1 reverse transcriptase to be cleaved by protease in virions.The NTD-CTD intersubunit interface plays a critical role in assembly and stabilization of the HIV-1 capsid.A temporospatial map that defines specific steps at which critical surfaces in the Gag MA and CA domains act during immature HIV-1 capsid assembly in cells.The host protein Staufen1 participates in human immunodeficiency virus type 1 assembly in live cells by influencing pr55Gag multimerization.Mutation in the loop C-terminal to the cyclophilin A binding site of HIV-1 capsid protein disrupts proper virus assembly and infectivity.Molecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity.Effect of internal cleavage site mutations in human immunodeficiency virus type 1 capsid protein on its structure and function.HIV Gag-leucine zipper chimeras form ABCE1-containing intermediates and RNase-resistant immature capsids similar to those formed by wild-type HIV-1 Gag.Mutations in HPV18 E1^E4 Impact Virus Capsid Assembly, Infectivity Competence, and Maturation.A risk for non-sexual transmission of human papillomavirus?Identifying the assembly intermediate in which Gag first associates with unspliced HIV-1 RNA suggests a novel model for HIV-1 RNA packaging.Formation of RNA Granule-Derived Capsid Assembly Intermediates Appears To Be Conserved between Human Immunodeficiency Virus Type 1 and the Nonprimate Lentivirus Feline Immunodeficiency Virus.
P2860
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P2860
Mutation of dileucine-like motifs in the human immunodeficiency virus type 1 capsid disrupts virus assembly, gag-gag interactions, gag-membrane binding, and virion maturation
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Mutation of dileucine-like mot ...... binding, and virion maturation
@ast
Mutation of dileucine-like mot ...... binding, and virion maturation
@en
type
label
Mutation of dileucine-like mot ...... binding, and virion maturation
@ast
Mutation of dileucine-like mot ...... binding, and virion maturation
@en
prefLabel
Mutation of dileucine-like mot ...... binding, and virion maturation
@ast
Mutation of dileucine-like mot ...... binding, and virion maturation
@en
P2093
P2860
P356
P1433
P1476
Mutation of dileucine-like mot ...... binding, and virion maturation
@en
P2093
Anjali Joshi
Eric O Freed
Kunio Nagashima
P2860
P304
P356
10.1128/JVI.00355-06
P407
P577
2006-08-01T00:00:00Z