PARP-2 regulates SIRT1 expression and whole-body energy expenditure - Wikidata - awgldk - TriplyDB

PARP-2 regulates SIRT1 expression and whole-body energy expenditure

PARP-2 regulates SIRT1 expression and whole-body energy expenditure

http://www.wikidata.org/entity/Q35026114

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Emerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disorders Sirtuin 1 and sirtuin 3: physiological modulators of metabolism Sirtuins as regulators of metabolism and healthspan Metabolic modulation of chromatin: implications for DNA repair and genomic integrity Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)?NAD+ as a signaling molecule modulating metabolism Mitochondrial proteostasis in the control of aging and longevity Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy The beneficial role of vitamin D in obesity: possible genetic and cell signaling mechanisms Redox regulation of SIRT1 in inflammation and cellular senescence Understanding specific functions of PARP-2: new lessons for cancer therapy Dysregulation of SIRT-1 in aging mice increases skeletal muscle fatigue by a PARP-1-dependent mechanism Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: a reevaluation Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.Big brains, meat, tuberculosis, and the nicotinamide switches: co-evolutionary relationships with modern repercussions?Analysis of knockout mutants reveals non-redundant functions of poly(ADP-ribose)polymerase isoforms in Arabidopsis Resveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis.The ways and means that fine tune Sirt1 activity.PARP inhibition delays progression of mitochondrial encephalopathy in mice.New facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases.Fine-tuning of Smad protein function by poly(ADP-ribose) polymerases and poly(ADP-ribose) glycohydrolase during transforming growth factor β signaling.The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.High-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression.Glycogen phosphorylase inhibitor N-(3,5-dimethyl-Benzoyl)-N'-(β-D-glucopyranosyl)urea improves glucose tolerance under normoglycemic and diabetic conditions and rearranges hepatic metabolism.Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism.Interference between PARPs and SIRT1: a novel approach to healthy ageing?Overexpression of SIRT1 in rat skeletal muscle does not alter glucose induced insulin resistance Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans.Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation.PARPs and ADP-Ribosylation: 50 Years … and Counting.NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors.DNA transcription and repair: a confluence NAD(+)/NADH and skeletal muscle mitochondrial adaptations to exercise.Exploring the therapeutic space around NAD+.The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.Mitochondrial sirtuins and metabolic homeostasis Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes.Parp-2 is required to maintain hematopoiesis following sublethal γ-irradiation in mice

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PARP-2 regulates SIRT1 expression and whole-body energy expenditure

http://www.wikidata.org/entity/Q35026114

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2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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name

PARP-2 regulates SIRT1 expression and whole-body energy expenditure

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PARP-2 regulates SIRT1 expression and whole-body energy expenditure

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type

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PARP-2 regulates SIRT1 expression and whole-body energy expenditure

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PARP-2 regulates SIRT1 expression and whole-body energy expenditure

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prefLabel

PARP-2 regulates SIRT1 expression and whole-body energy expenditure

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PARP-2 regulates SIRT1 expression and whole-body energy expenditure

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J.CMET.2011.03.013

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Cell Metabolism

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PARP-2 regulates SIRT1 expression and whole-body energy expenditure

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Aline Huber

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Anthony A Sauve

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Attila Brunyánszki

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Borbala Kiss

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Hiroyasu Yamamoto

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Hugues Oudart

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Josiane Menissier-de Murcia

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Magdolna Szántó

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Pál Gergely

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Péter Bai

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P2860

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers.

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth

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450-460

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10.1016/J.CMET.2011.03.013

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4

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2011-04-01T00:00:00Z

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50988294

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21459329

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3108571

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