Therapeutic role of mammalian target of rapamycin (mTOR) inhibition in preventing epileptogenesis.
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The ketogenic diet as a treatment paradigm for diverse neurological disordersEpilepsy related to developmental tumors and malformations of cortical developmentLow-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver diseaseSpatiotemporal characterization of mTOR kinase activity following kainic acid induced status epilepticus and analysis of rat brain response to chronic rapamycin treatmentMapping the spatio-temporal pattern of the mammalian target of rapamycin (mTOR) activation in temporal lobe epilepsyGene expression profiling of a hypoxic seizure model of epilepsy suggests a role for mTOR and Wnt signaling in epileptogenesis.Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of tuberous sclerosis.The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments.AMPA receptor antagonist NBQX attenuates later-life epileptic seizures and autistic-like social deficits following neonatal seizuresUnderstanding relationships between autism, intelligence, and epilepsy: a cross-disorder approach.Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction.Evidence for mTOR pathway activation in a spectrum of epilepsy-associated pathologies.Rapamycin down-regulates KCC2 expression and increases seizure susceptibility to convulsants in immature rats.Inhibition of mTOR Pathway by Rapamycin Reduces Brain Damage in Rats Subjected to Transient Forebrain Ischemia.Rapamycin has age-, treatment paradigm-, and model-specific anticonvulsant effects and modulates neuropeptide Y expression in rats.Mammalian target of rapamycin (mTOR) inhibition: potential for antiseizure, antiepileptogenic, and epileptostatic therapy.A critical review of mTOR inhibitors and epilepsy: from basic science to clinical trials.Mammalian target of rapamycin (mTOR) pathways in neurological diseases.Epilepsy Mechanisms in Neurocutaneous Disorders: Tuberous Sclerosis Complex, Neurofibromatosis Type 1, and Sturge-Weber Syndrome.The mTOR signaling pathway in the brain: focus on epilepsy and epileptogenesis.mTOR inhibitors as a new therapeutic option for epilepsy.Are vesicular neurotransmitter transporters potential treatment targets for temporal lobe epilepsy?mTOR as a potential treatment target for epilepsy.New strategies for preventing epileptogenesis: perspective and overview.Effects of thymoquinone, the major constituent of Nigella sativa seeds, on penicillin-induced epileptiform activity in rats.Posttraumatic Epilepsy: What's Contusion Got to Do With It?Peroxisome proliferator-activated receptor-γ agonist inhibits the mammalian target of rapamycin signaling pathway and has a protective effect in a rat model of status epilepticus.PI3K-Akt signaling activates mTOR-mediated epileptogenesis in organotypic hippocampal culture model of post-traumatic epilepsy.Prion-like mechanisms in epileptogenesis.In vivo imaging of glia activation using 1H-magnetic resonance spectroscopy to detect putative biomarkers of tissue epileptogenicity.TORC1-dependent epilepsy caused by acute biallelic Tsc1 deletion in adult mice.BRAF V600E mutation is associated with mTOR signaling activation in glioneuronal tumors.Commonalities in epileptogenic processes from different acute brain insults: Do they translate?Epilepsy as a Network Disorder (2): What can we learn from other network disorders such as dementia and schizophrenia, and what are the implications for translational research?Effects of rapamycin and curcumin treatment on the development of epilepsy after electrically induced status epilepticus in rats.Effects of rapamycin and curcumin on inflammation and oxidative stress in vitro and in vivo - in search of potential anti-epileptogenic strategies for temporal lobe epilepsy
P2860
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P2860
Therapeutic role of mammalian target of rapamycin (mTOR) inhibition in preventing epileptogenesis.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Therapeutic role of mammalian ...... in preventing epileptogenesis.
@ast
Therapeutic role of mammalian ...... in preventing epileptogenesis.
@en
type
label
Therapeutic role of mammalian ...... in preventing epileptogenesis.
@ast
Therapeutic role of mammalian ...... in preventing epileptogenesis.
@en
prefLabel
Therapeutic role of mammalian ...... in preventing epileptogenesis.
@ast
Therapeutic role of mammalian ...... in preventing epileptogenesis.
@en
P2860
P1433
P1476
Therapeutic role of mammalian ...... in preventing epileptogenesis.
@en
P2093
Michael Wong
Sharon S McDaniel
P2860
P304
P356
10.1016/J.NEULET.2011.02.037
P407
P577
2011-02-24T00:00:00Z