The dynamic conformational landscape of gamma-secretase.
about
Current and future implications of basic and translational research on amyloid-β peptide production and removal pathwaysAn atomic structure of human γ-secretaseStructural basis of human γ-secretase assembly.Substrate recruitment of γ-secretase and mechanism of clinical presenilin mutations revealed by photoaffinity mapping.Interrelationship between changes in the amyloid β 42/40 ratio and presenilin 1 conformationPhysiological and pathological roles of the γ-secretase complex.Dynamic Nature of presenilin1/γ-Secretase: Implication for Alzheimer's Disease Pathogenesis.Characterizing the structural ensemble of γ-secretase using a multiscale molecular dynamics approachHigh-efficient production and biophysical characterisation of nicastrin and its interaction with APPC100Probing γ-secretase-substrate interactions at the single amino acid residue level.Backbone Hydrogen Bond Strengths Can Vary Widely in Transmembrane Helices.Influence of solubilization and AD-mutations on stability and structure of human presenilins.Allosteric Modulation of Intact γ-Secretase Structural Dynamics.Structural and Chemical Biology of Presenilin Complexes.Integrative structure and functional anatomy of a nuclear pore complex.Efficient production of a mature and functional gamma secretase protease
P2860
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P2860
The dynamic conformational landscape of gamma-secretase.
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
The dynamic conformational landscape of gamma-secretase.
@ast
The dynamic conformational landscape of gamma-secretase.
@en
type
label
The dynamic conformational landscape of gamma-secretase.
@ast
The dynamic conformational landscape of gamma-secretase.
@en
prefLabel
The dynamic conformational landscape of gamma-secretase.
@ast
The dynamic conformational landscape of gamma-secretase.
@en
P2093
P2860
P50
P356
P1476
The dynamic conformational landscape of gamma-secretase
@en
P2093
Bart De Strooper
Katrien Horré
Lucía Chávez-Gutiérrez
Muriel Arimon
Oksana Berezovska
Sam Lismont
Sarah Veugelen
P2860
P304
P356
10.1242/JCS.164384
P407
P577
2015-02-01T00:00:00Z