Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice. - Wikidata - awgldk - TriplyDB

Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice.

Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice.

http://www.wikidata.org/entity/Q35030142

about

Emerging targets in lipid-based therapy Inflammation-induced dysfunction of the low-density lipoprotein receptor-related protein-1 at the blood-brain barrier: protection by the antioxidant N-acetylcysteine.Mixed oligomers and monomeric amyloid-β disrupts endothelial cells integrity and reduces monomeric amyloid-β transport across hCMEC/D3 cell line as an in vitro blood-brain barrier model.Alzheimer's and ABC transporters--new opportunities for diagnostics and treatment.ABC Transporters and the Alzheimer's Disease Enigma.High-Throughput Screening for Identification of Blood-Brain Barrier Integrity Enhancers: A Drug Repurposing Opportunity to Rectify Vascular Amyloid Toxicity.Aβ1-42 reduces P-glycoprotein in the blood-brain barrier through RAGE-NF-κB signaling.Role of ABC transporters in the pathogenesis of Alzheimer's disease Aβ40 Reduces P-Glycoprotein at the Blood-Brain Barrier through the Ubiquitin-Proteasome Pathway.Early brain injury alters the blood-brain barrier phenotype in parallel with β-amyloid and cognitive changes in adulthood Blood-brain barrier transport of amyloid beta peptides in efflux pump knock-out animals evaluated by in vivo optical imaging.Blood-brain barrier dysfunction as a cause and consequence of Alzheimer's disease.The role of inflammatory processes in Alzheimer's disease.Pregnane X Receptor and P-glycoprotein: a connexion for Alzheimer's disease management.Drug access to the central nervous system in Alzheimer's disease: preclinical and clinical insights.Transporters as Drug Targets in Neurological Diseases Age-associated physiological and pathological changes at the blood-brain barrier: A review.Increased expression of the receptor for advanced glycation end-products in human peripheral neuropathies.Association of ATP-binding cassette transporter variants with the risk of Alzheimer's disease.Aging alters mRNA expression of amyloid transporter genes at the blood-brain barrier.Vitamin D Supplementation Appears to Increase Plasma Aβ40 in Vitamin D Insufficient Older Adults: A Pilot Randomized Controlled Trial.Modulation of the ATP-Binding Cassette B1 Transporter by Neuro-Inflammatory Cytokines: Role in the Pathogenesis of Alzheimer's Disease.

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P2860

Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice.

http://www.wikidata.org/entity/Q35030142

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Beta-Amyloid Downregulates MDR ...... e Blood-Brain Barrier in Mice.

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Beta-Amyloid Downregulates MDR ...... e Blood-Brain Barrier in Mice.

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International journal of Alzheimer's disease

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Beta-Amyloid Downregulates MDR ...... e Blood-Brain Barrier in Mice.

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P2093

Andrea Fischer

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Anja Brenn

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Gabriele Jedlitschky

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Heyo K Kroemer

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Markus Grube

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Michele Peters

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Rolf W Warzok

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Silke Vogelgesang

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P2860

beta-Amyloid efflux mediated by p-glycoprotein.

Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

Multidrug resistance transporters and modulation.

The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia

Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.

ABCG2: a perspective.

Amyloid beta-peptide [1-42]-associated free radical-induced oxidative stress and neurodegeneration in Alzheimer's disease brain: mechanisms and consequences.

Functional expression and localization of P-glycoprotein in the central nervous system: relevance to the pathogenesis and treatment of neurological disorders.

Neurovascular mechanisms of Alzheimer's neurodegeneration.

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10.4061/2011/690121

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2011

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2011-05-29T00:00:00Z

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51207640

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blood–brain barrier

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3109772

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