Prostate tumor-stroma interaction: molecular mechanisms and opportunities for therapeutic targeting.
about
Haploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostateCoevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis.Met-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells.Analysis of gene expression in prostate cancer epithelial and interstitial stromal cells using laser capture microdissection.CD90/THY1 is overexpressed in prostate cancer-associated fibroblasts and could serve as a cancer biomarker.Gene targeting to the stroma of the prostate and bone.Role of the adjacent stroma cells in prostate cancer development and progression: synergy between TGF-β and IGF signaling.Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts.Normal peripheral prostate stromal cells stimulate prostate cancer development: roles of c-kit signalRegulation of androgen receptor signaling in prostate cancer.Future perspectives of prostate cancer therapy.New therapeutic approach to suppress castration-resistant prostate cancer using ASC-J9 via targeting androgen receptor in selective prostate cells.Genetic deletion of osteopontin in TRAMP mice skews prostate carcinogenesis from adenocarcinoma to aggressive human-like neuroendocrine cancers.Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent mannerTumor formation of prostate cancer cells influenced by stromal cells from the transitional or peripheral zones of the normal prostate.The differential effects of prostate stromal cells derived from different zones on prostate cancer epithelial cells under the action of sex hormonesActivin receptor signaling regulates prostatic epithelial cell adhesion and viability.Stromagenesis during tumorigenesis: characterization of tumor-associated fibroblasts and stroma-derived 3D matrices.Prostate cancer cell telomere length variability and stromal cell telomere length as prognostic markers for metastasis and death.Protease-activated receptor-1 is upregulated in reactive stroma of primary prostate cancer and bone metastasis.Bone marrow stromal cells enhance prostate cancer cell invasion through type I collagen in an MMP-12 dependent manner.Antisense-MDM2 sensitizes LNCaP prostate cancer cells to androgen deprivation, radiation, and the combination in vivo.Chemical and Biochemical Basis of Cell-Bone Matrix Interaction in Health and Disease.ARP2, a novel pro-apoptotic protein expressed in epithelial prostate cancer LNCaP cells and epithelial ovary CHO transformed cells.Loss of TGF-β responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions.Role of the EpCAM (CD326) in prostate cancer metastasis and progression.Expression signature of the mouse prostate.Progressive epithelial to mesenchymal transitions in ARCaP E prostate cancer cells during xenograft tumor formation and metastasis.Oxidative stress induced autophagy in cancer associated fibroblast enhances proliferation and metabolism of colorectal cancer cells.Matched pairs of human prostate stromal cells display differential tropic effects on LNCaP prostate cancer cells.Differential Inductive Signaling of CD90 Prostate Cancer-Associated Fibroblasts Compared to Normal Tissue Stromal Mesenchyme Cells.31P magnetic resonance spectroscopy of endothelial cells grown in three-dimensional matrigel construct as an enabling platform technology: I. The effect of glial cells and valproic acid on phosphometabolite levels.Cotargeting tumor and tumor endothelium effectively inhibits the growth of human prostate cancer in adenovirus-mediated antiangiogenesis and oncolysis combination therapy.Expression of IL-17A, E, and F and their receptors in human prostatic cancer: Comparison with benign prostatic hyperplasia.Interleukin 6 mediates the lysophosphatidic acid-regulated cross-talk between stromal and epithelial prostate cancer cells.Cotargeting tumor and stroma in a novel chimeric tumor model involving the growth of both human prostate cancer and bone stromal cells.Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer.The shed ectodomain of type XIII collagen associates with the fibrillar fibronectin matrix and may interfere with its assembly in vitro.Human periprostatic adipose tissue promotes prostate cancer aggressiveness in vitro.Inhibition of epithelial ductal branching in the prostate by sonic hedgehog is indirectly mediated by stromal cells.
P2860
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P2860
Prostate tumor-stroma interaction: molecular mechanisms and opportunities for therapeutic targeting.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Prostate tumor-stroma interact ...... ies for therapeutic targeting.
@ast
Prostate tumor-stroma interact ...... ies for therapeutic targeting.
@en
type
label
Prostate tumor-stroma interact ...... ies for therapeutic targeting.
@ast
Prostate tumor-stroma interact ...... ies for therapeutic targeting.
@en
prefLabel
Prostate tumor-stroma interact ...... ies for therapeutic targeting.
@ast
Prostate tumor-stroma interact ...... ies for therapeutic targeting.
@en
P1433
P1476
Prostate tumor-stroma interact ...... ies for therapeutic targeting.
@en
P2093
Leland W K Chung
Shian-Ying Sung
P304
P356
10.1046/J.1432-0436.2002.700905.X
P577
2002-12-01T00:00:00Z