Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor.
about
'Acute myeloid leukemia: a comprehensive review and 2016 update'Diminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxisIcariside II induces apoptosis in U937 acute myeloid leukemia cells: role of inactivation of STAT3-related signalingSTAT inhibitors for cancer therapy.Cucurbitacin I induces protective autophagy in glioblastoma in vitro and in vivoRas oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia.Stromal CYR61 Confers Resistance to Mitoxantrone via Spleen Tyrosine Kinase Activation in Human Acute Myeloid LeukaemiaAntineoplastic effects of CPPTL via the ROS/JNK pathway in acute myeloid leukemia.Signal transducer and activator of transcription 3 (STAT3) gene polymorphisms are associated with treatment outcomes in acute myeloid leukemia.Safety and pharmacokinetics of the antisense oligonucleotide (ASO) LY2181308 as a single-agent or in combination with idarubicin and cytarabine in patients with refractory or relapsed acute myeloid leukemia (AML)TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivoCalpain/SHP-1 interaction by honokiol dampening peritoneal dissemination of gastric cancer in nu/nu miceResveratrol induces cell cycle arrest and apoptosis in malignant NK cells via JAK2/STAT3 pathway inhibitionStat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinomaMechanisms of muscle wasting in chronic kidney diseaseMEK/ERK dependent activation of STAT1 mediates dasatinib-induced differentiation of acute myeloid leukemia.A novel missense (M206K) STAT3 mutation in diffuse large B cell lymphoma deregulates STAT3 signalingHigh expression of suppressor of cytokine signaling-2 predicts poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group.Inhibition of Stat3 activation suppresses caspase-3 and the ubiquitin-proteasome system, leading to preservation of muscle mass in cancer cachexiaExpression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulationA truncation mutant of Csf3r cooperates with PML-RARα to induce acute myeloid leukemia in mice.Enhancing SHP-1 expression with 5-azacytidine may inhibit STAT3 activation and confer sensitivity in lestaurtinib (CEP-701)-resistant FLT3-ITD positive acute myeloid leukemia.Targeting the interleukin-6/Jak/stat pathway in human malignanciesSmall-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer.Cell cycle control in acute myeloid leukemia.Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterationsTargeting Stat3 abrogates EGFR inhibitor resistance in cancer.STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation.FACS analysis of Stat3/5 signaling reveals sensitivity to G-CSF and IL-6 as a significant prognostic factor in pediatric AML: a Children's Oncology Group reportSerum-resistant CpG-STAT3 decoy for targeting survival and immune checkpoint signaling in acute myeloid leukemia.A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemiaTargeting STAT3 inhibits growth and enhances radiosensitivity in head and neck squamous cell carcinomaNotch signalling drives bone marrow stromal cell-mediated chemoresistance in acute myeloid leukemiaRhodium(II) Proximity-Labeling Identifies a Novel Target Site on STAT3 for Inhibitors with Potent Anti-Leukemia Activity.Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinomaTargeting the link between late pregnancy and breast cancer.Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy.Leukemia cell-targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity.Inflammation: what role in pediatric cancer?STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.
P2860
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P2860
Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Stat3 signaling in acute myelo ...... mall-molecule Stat3 inhibitor.
@ast
Stat3 signaling in acute myelo ...... mall-molecule Stat3 inhibitor.
@en
type
label
Stat3 signaling in acute myelo ...... mall-molecule Stat3 inhibitor.
@ast
Stat3 signaling in acute myelo ...... mall-molecule Stat3 inhibitor.
@en
prefLabel
Stat3 signaling in acute myelo ...... mall-molecule Stat3 inhibitor.
@ast
Stat3 signaling in acute myelo ...... mall-molecule Stat3 inhibitor.
@en
P2093
P2860
P1433
P1476
Stat3 signaling in acute myelo ...... mall-molecule Stat3 inhibitor.
@en
P2093
David J Tweardy
Marcos J Ruiz
Michele S Redell
Robert B Gerbing
Todd A Alonzo
P2860
P304
P356
10.1182/BLOOD-2010-04-280123
P407
P577
2011-03-29T00:00:00Z