Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity.
about
Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic TargetsTumour Cell HeterogeneityThe TWEAK receptor Fn14 is a potential cell surface portal for targeted delivery of glioblastoma therapeuticsCancer stem cells and the tumor microenvironment: interplay in tumor heterogeneityEvolutionary determinants of cancerMolecular heterogeneity in glioblastoma: potential clinical implicationsOvercoming therapeutic resistance in glioblastoma: the way forwardCancer stem cell heterogeneity: origin and new perspectives on CSC targetingMRI-Guided Stereotactic Biopsy of Murine GBM for Spatiotemporal Molecular Genomic AssessmentContribution of the Microenvironmental Niche to Glioblastoma Heterogeneity.Cancer stem cells in glioblastomaAtracurium Besylate and other neuromuscular blocking agents promote astroglial differentiation and deplete glioblastoma stem cellsThe Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes.g:Profiler-a web server for functional interpretation of gene lists (2016 update)Intratumoral heterogeneity in glioblastoma: don't forget the peritumoral brain zone.Single-cell sequencing maps gene expression to mutational phylogenies in PDGF- and EGF-driven gliomasHistologically defined intratumoral sequencing uncovers evolutionary cues into conserved molecular events driving gliomagenesis.Chromosomal Instability Affects the Tumorigenicity of Glioblastoma Tumor-Initiating Cells.Temozolomide promotes genomic and phenotypic changes in glioblastoma cells.A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo.Label-retaining assay enriches tumor-initiating cells in glioblastoma spheres cultivated in serum-free medium.Systematic characterization of lncRNAs' cell-to-cell expression heterogeneity in glioblastoma cells.Inhibition of mitochondrial 2-oxoglutarate dehydrogenase impairs viability of cancer cells in a cell-specific metabolism-dependent manner.ER stress in temozolomide-treated glioblastomas interferes with DNA repair and induces apoptosis.Characterization of the CD49f+/CD44+/CD24- single-cell derived stem cell population in basal-like DCIS cells.Cancer stem cells from human glioblastoma resemble but do not mimic original tumors after in vitro passaging in serum-free media.A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in gliomaToward precision medicine in glioblastoma: the promise and the challenges.Emerging circulating biomarkers in glioblastoma: promises and challenges.Emerging Proteomic Technologies Provide Enormous and Underutilized Potential for Brain Cancer Research.Glioblastoma targeted therapy: updated approaches from recent biological insights.Single-cell approaches for molecular classification of endocrine tumors.An epigenetic gateway to brain tumor cell identity.Evidence of drug-response heterogeneity rapidly generated from a single cancer cell.Integrative functional genomic analysis identifies epigenetically regulated fibromodulin as an essential gene for glioma cell migration.Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells.Extracellular Vesicles and MicroRNAs: Their Role in Tumorigenicity and Therapy for Brain Tumors.Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma.Phenotypic Transition as a Survival Strategy of Glioma.Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma.
P2860
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P2860
Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Single cell-derived clonal ana ...... nal and genomic heterogeneity.
@ast
Single cell-derived clonal ana ...... nal and genomic heterogeneity.
@en
type
label
Single cell-derived clonal ana ...... nal and genomic heterogeneity.
@ast
Single cell-derived clonal ana ...... nal and genomic heterogeneity.
@en
prefLabel
Single cell-derived clonal ana ...... nal and genomic heterogeneity.
@ast
Single cell-derived clonal ana ...... nal and genomic heterogeneity.
@en
P2093
P2860
P50
P356
P1476
Single cell-derived clonal ana ...... nal and genomic heterogeneity.
@en
P2093
Anath C Lionel
Ian D Clarke
Jane Bayani
Jeremy A Squire
Jessica C Pressey
Mark Bernstein
Michael Cusimano
Michelle Kushida
Mona Meyer
Peter B Dirks
P2860
P304
P356
10.1073/PNAS.1320611111
P407
P577
2015-01-05T00:00:00Z