Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases. - Wikidata - awgldk - TriplyDB

Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases.

Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases.

http://www.wikidata.org/entity/Q35034984

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An evolutionary perspective on the kinome of malaria parasites The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18 A Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma Virulence Secreted effectors in Toxoplasma gondii and related species: determinants of host range and pathogenesis?A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins The Irish potato famine pathogen Phytophthora infestans translocates the CRN8 kinase into host plant cells Compensatory dendritic cell development mediated by BATF-IRF interactions Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity Prediction and Prevention of Parasitic Diseases Using a Landscape Genomics Framework.Is Toxoplasma gondii type related to clinical outcome in human congenital infection? Systematic and critical review.A focused small-molecule screen identifies 14 compounds with distinct effects on Toxoplasma gondii.Serum Albumin Stimulates Protein Kinase G-dependent Microneme Secretion in Toxoplasma gondii Toxoplasma gondii merozoite gene expression analysis with comparison to the life cycle discloses a unique expression state during enteric development The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice.Modulation of innate immunity by Toxoplasma gondii virulence effectors.Toxoplasma gondii development of its replicative niche: in its host cell and beyond.Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance Geographic separation of domestic and wild strains of Toxoplasma gondii in French Guiana correlates with a monomorphic version of chromosome1a.The Toxoplasma pseudokinase ROP5 is an allosteric inhibitor of the immunity-related GTPases.Subversion of host cellular functions by the apicomplexan parasites.The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.Hammondia hammondi, an avirulent relative of Toxoplasma gondii, has functional orthologs of known T. gondii virulence genes Distinct strains of Toxoplasma gondii feature divergent transcriptomes regardless of developmental stage.Hammondia hammondi harbors functional orthologs of the host-modulating effectors GRA15 and ROP16 but is distinguished from Toxoplasma gondii by a unique transcriptional profile.Have it your way: how polymorphic, injected kinases and pseudokinases enable Toxoplasma to subvert host defenses.Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.Structural and evolutionary adaptation of rhoptry kinases and pseudokinases, a family of coccidian virulence factors Genetic mapping reveals that sinefungin resistance in Toxoplasma gondii is controlled by a putative amino acid transporter locus that can be used as a negative selectable marker.Genetic manipulation of the Toxoplasma gondii genome by fosmid recombineering.Transcriptional analysis of murine macrophages infected with different Toxoplasma strains identifies novel regulation of host signaling pathways Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination.Toxoplasma gondii effectors are master regulators of the inflammatory response.Identification of tissue cyst wall components by transcriptome analysis of in vivo and in vitro Toxoplasma gondii bradyzoites A single chromosome unexpectedly links highly divergent isolates of Toxoplasma gondii.New method for the orthogonal labeling and purification of Toxoplasma gondii proteins while inside the host cell Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii.miR-146a and miR-155 delineate a MicroRNA fingerprint associated with Toxoplasma persistence in the host brain.Variation detection based on next-generation sequencing of type Chinese 1 strains of Toxoplasma gondii with different virulence from China.Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages.

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Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases.

http://www.wikidata.org/entity/Q35034984

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2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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Virulence differences in Toxop ...... of polymorphic pseudokinases.

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Virulence differences in Toxop ...... of polymorphic pseudokinases.

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Virulence differences in Toxop ...... of polymorphic pseudokinases.

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Virulence differences in Toxop ...... of polymorphic pseudokinases.

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Virulence differences in Toxop ...... of polymorphic pseudokinases.

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Virulence differences in Toxop ...... of polymorphic pseudokinases.

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Asis Khan

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John C Wootton

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Keliang Tang

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Michael S Behnke

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P2860

Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii

Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii.

ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity

Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii

Clustal W and Clustal X version 2.0

Median-joining networks for inferring intraspecific phylogenies

PAML 4: phylogenetic analysis by maximum likelihood

Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification

Tagging of endogenous genes in a Toxoplasma gondii strain lacking Ku80

Modelling parasite dissemination: host cell subversion and immune evasion by Toxoplasma gondii.

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