Should evolutionary geneticists worry about higher-order epistasis? - Wikidata - awgldk - TriplyDB

Should evolutionary geneticists worry about higher-order epistasis?

Should evolutionary geneticists worry about higher-order epistasis?

http://www.wikidata.org/entity/Q35035921

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What can we learn from fitness landscapes?Strong Selection Significantly Increases Epistatic Interactions in the Long-Term Evolution of a Protein Adaptive Landscape by Environment Interactions Dictate Evolutionary Dynamics in Models of Drug Resistance A New Take on John Maynard Smith's Concept of Protein Space for Understanding Molecular Evolution Detecting High-Order Epistasis in Nonlinear Genotype-Phenotype Maps The role of functional data in interpreting the effects of genetic variation Enzyme Efficiency but Not Thermostability Drives Cefotaxime Resistance Evolution in TEM-1 β-Lactamase.Stability-Mediated Epistasis Restricts Accessible Mutational Pathways in the Functional Evolution of Avian Hemoglobin.Inferring fitness landscapes by regression produces biased estimates of epistasis.Causes of molecular convergence and parallelism in protein evolution.HiSeeker: Detecting High-Order SNP Interactions Based on Pairwise SNP Combinations.Systems biology and the analysis of genetic variation.Higher-order genetic interactions and their contribution to complex traits.Properties of selected mutations and genotypic landscapes under Fisher's geometric model.Multidimensional epistasis and the transitory advantage of sex.Protein evolution. Pervasive degeneracy and epistasis in a protein-protein interface.Quantitative Description of a Protein Fitness Landscape Based on Molecular Features.A Bayesian model for detection of high-order interactions among genetic variants in genome-wide association studies Coupling high-throughput genetics with phylogenetic information reveals an epistatic interaction on the influenza A virus M segment.Identification of cis-suppression of human disease mutations by comparative genomics.Survival of the Curviest: Noise-Driven Selection for Synergistic Epistasis.The Context-Dependence of Mutations: A Linkage of Formalisms.Epistasis and Entropy Changing preferences: deformation of single position amino acid fitness landscapes and evolution of proteins High-order epistasis shapes evolutionary trajectories.A pivot mutation impedes reverse evolution across an adaptive landscape for drug resistance in Plasmodium vivax Neighboring genes for DNA-binding proteins rescue male sterility in Drosophila hybrids.Local fitness landscape of the green fluorescent protein.Adaptation in protein fitness landscapes is facilitated by indirect paths Causes and consequences of genetic background effects illuminated by integrative genomic analysis.Empirical fitness landscapes and the predictability of evolution.Genetic variation in adaptability and pleiotropy in budding yeast.Epistasis in protein evolution.Genotypic Complexity of Fisher's Geometric Model.Genotypic Context and Epistasis in Individuals and Populations.Bridging the physical scales in evolutionary biology: from protein sequence space to fitness of organisms and populations.Spiraling Complexity: A Test of the Snowball Effect in a Computational Model of RNA Folding.Evolutionary interplay between structure, energy and epistasis in the coat protein of the ϕX174 phage family.Effect of host species on the topography of fitness landscape for a plant RNA virus.Epistasis and the Structure of Fitness Landscapes: Are Experimental Fitness Landscapes Compatible with Fisher's Geometric Model?

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Should evolutionary geneticists worry about higher-order epistasis?

http://www.wikidata.org/entity/Q35035921

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2013 nî lūn-bûn

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2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Should evolutionary geneticists worry about higher-order epistasis?

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Should evolutionary geneticists worry about higher-order epistasis?

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Should evolutionary geneticists worry about higher-order epistasis?

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Should evolutionary geneticists worry about higher-order epistasis?

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Should evolutionary geneticists worry about higher-order epistasis?

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J.GDE.2013.10.007

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Current Opinion in Genetics & Development

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Should evolutionary geneticists worry about higher-order epistasis?

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C Scott Wylie

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Daniel M Weinreich

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Robert B Heckendorn

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Yinghong Lan

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P2860

Protein 3D structure computed from evolutionary sequence variation

EVOLUTION OF SEXRESOLVING THE PARADOX OF SEX AND RECOMBINATION

Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

Dobzhansky, Bateson, and the genetics of speciation

Direct-coupling analysis of residue coevolution captures native contacts across many protein families

Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases

Mechanisms for the Evolution of a Derived Function in the Ancestral Glucocorticoid Receptor

The genetic landscape of a cell

Protein sectors: evolutionary units of three-dimensional structure

Fitness trade-offs in the evolution of dihydrofolate reductase and drug resistance in Plasmodium falciparum

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