The P2Y(1) receptor closes the N-type Ca(2+) channel in neurones, with both adenosine triphosphates and diphosphates as potent agonists.
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International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapyP2Y Receptors in Synaptic Transmission and Plasticity: Therapeutic Potential in Cognitive Dysfunction.Activity of adenosine diphosphates and triphosphates on a P2Y(T) -type receptor in brain capillary endothelial cellsCharacterization and channel coupling of the P2Y(12) nucleotide receptor of brain capillary endothelial cellsAnalyzing receptor assemblies in the cell membrane using fluorescence anisotropy imaging with TIRF microscopyP2Y1 receptor signaling is controlled by interaction with the PDZ scaffold NHERF-2ADP-induced bladder contractility is mediated by P2Y12 receptor and temporally regulated by ectonucleotidases and adenosine signaling.Coupling of the nucleotide P2Y4 receptor to neuronal ion channelsAdenine nucleotides inhibit recombinant N-type calcium channels via G protein-coupled mechanisms in HEK 293 cells; involvement of the P2Y13 receptor-type.Regulation of neuronal ion channels via P2Y receptors.Release of ATP by pre-Bötzinger complex astrocytes contributes to the hypoxic ventilatory response via a Ca2+ -dependent P2Y1 receptor mechanism.The scaffold protein NHERF2 determines the coupling of P2Y1 nucleotide and mGluR5 glutamate receptor to different ion channels in neurons.P2X receptor subtype-specific modulation of excitatory and inhibitory synaptic inputs in the rat brainstem.Membrane coordination of receptors and channels mediating the inhibition of neuronal ion currents by ADP.Inhibition of adenylyl cyclase by neuronal P2Y receptors.Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networksA mechanism for nerve cell excitation by norepinephrine via α-1 adrenoceptors: inhibition of potassium M-currentAgonists of the P2Y(AC)-receptor activate MAP kinase by a ras-independent pathway in rat C6 glioma.P2Y1 receptors mediate an activation of neuronal calcium-dependent K+ channels.Attenuation of the P2Y receptor-mediated control of neuronal Ca2+ channels in PC12 cells by antithrombotic drugs.The pharmacology of nucleotide receptors on primary rat brain endothelial cells grown on a biological extracellular matrix: effects on intracellular calcium concentration.P2Y receptor-mediated inhibition of voltage-activated Ca(2+) currents in PC12 cells.Adenosine nucleotides acting at the human P2Y1 receptor stimulate mitogen-activated protein kinases and induce apoptosis.Interaction between ATP and catecholamines in stimulation of platelet aggregation.Purinergic modulation of norepinephrine release and uptake in rat brain cortex: contribution of glial cells.
P2860
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P2860
The P2Y(1) receptor closes the N-type Ca(2+) channel in neurones, with both adenosine triphosphates and diphosphates as potent agonists.
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2000 nî lūn-bûn
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name
The P2Y(1) receptor closes the ...... phosphates as potent agonists.
@en
type
label
The P2Y(1) receptor closes the ...... phosphates as potent agonists.
@en
prefLabel
The P2Y(1) receptor closes the ...... phosphates as potent agonists.
@en
P2093
P2860
P356
P1476
The P2Y(1) receptor closes the ...... phosphates as potent agonists.
@en
P2093
A K Filippov
E A Barnard
P2860
P304
P356
10.1038/SJ.BJP.0703185
P407
P577
2000-03-01T00:00:00Z