Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition.
about
RASopathies: unraveling mechanisms with animal modelsVariation of mutant allele frequency in NRAS Q61 mutated melanomas.Drugging the undruggable RAS: Mission possible?NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.Evolving molecularly targeted therapies for advanced-stage thyroid cancers.Modeling RASopathies with Genetically Modified Mouse Models.Farnesyltransferase-Mediated Delivery of a Covalent Inhibitor Overcomes Alternative Prenylation to Mislocalize K-Ras.Concepts and advances in cancer therapeutic vulnerabilities in RAS membrane targeting.Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene.Paternal uniparental disomy 11p15.5 in the pancreatic nodule of an infant with Costello syndrome: Shared mechanism for hyperinsulinemic hypoglycemia in neonates with Costello and Beckwith-Wiedemann syndrome and somatic loss of heterozygosity in CostIsoprenoids and protein prenylation: implications in the pathogenesis and therapeutic intervention of Alzheimer's disease.
P2860
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P2860
Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition.
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Transformation by Hras(G12V) i ...... rnesyl transferase inhibition.
@en
type
label
Transformation by Hras(G12V) i ...... rnesyl transferase inhibition.
@en
prefLabel
Transformation by Hras(G12V) i ...... rnesyl transferase inhibition.
@en
P2093
P2860
P356
P1433
P1476
Transformation by Hras(G12V) i ...... arnesyl transferase inhibition
@en
P2093
J M Makarewicz
L K Johnson
P2860
P2888
P304
P356
10.1038/ONC.2013.489
P407
P577
2013-11-18T00:00:00Z