Hypophosphatemia: mouse model for human familial hypophosphatemic (vitamin D-resistant) rickets.
about
Cloning of human PEX cDNA. Expression, subcellular localization, and endopeptidase activityDegradation of MEPE, DMP1, and release of SIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYPWhat use is the human genome for understanding the mouse?Fibroblast Growth Factor 23: A New Dimension to Diseases of Calcium-Phosphorus MetabolismProtective roles of DMP1 in high phosphate homeostasisIncreased renal catabolism of 1,25-dihydroxyvitamin D3 in murine X-linked hypophosphatemic ricketsTargeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalitiesAmelogenesis imperfecta and other biomineralization defects in Fam20a and Fam20c null miceSpermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine.The Gy mutation: another cause of X-linked hypophosphatemia in mouse.X-linked hypophosphatemia: the mutant gene is expressed in teeth as well as in kidneyIsolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.Nuclear isoforms of fibroblast growth factor 2 are novel inducers of hypophosphatemia via modulation of FGF23 and KLOTHOIncreased bone volume and correction of HYP mouse hypophosphatemia in the Klotho/HYP mouse.Identification of a novel dentin matrix protein-1 (DMP-1) mutation and dental anomalies in a kindred with autosomal recessive hypophosphatemia.New intragenic deletions in the Phex gene clarify X-linked hypophosphatemia-related abnormalities in mice.Defective binding of macrophages to bone in rodent osteomalacia and vitamin D deficiency. In vitro evidence for a cellular defect and altered saccharides in the bone matrix.Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes.Expression and distribution of SIBLING proteins in the predentin/dentin and mandible of hyp mice.The molecular background to hypophosphataemic rickets.Tissue-nonspecific alkaline phosphatase deficiency causes abnormal craniofacial bone development in the Alpl(-/-) mouse model of infantile hypophosphatasiaRenal Na(+)-phosphate cotransport in murine X-linked hypophosphatemic rickets. Molecular characterizationX-linked spermine synthase gene (SMS) defect: the first polyamine deficiency syndrome.Cellular ATP synthesis mediated by type III sodium-dependent phosphate transporter Pit-1 is critical to chondrogenesisAbnormal parathyroid hormone stimulation of 25-hydroxyvitamin D-1 alpha-hydroxylase activity in the hypophosphatemic mouse. Evidence for a generalized defect of vitamin D metabolism.Autosomal hypophosphataemic bone disease responds to 1,25-(OH)2D3.Genetically altered mouse models: the good, the bad, and the ugly.The William Allan Memorial Award address: On phosphate transport and genetic screening. "Understanding backward--living forward" in human genetics.Mutational analysis of the PEX gene in patients with X-linked hypophosphatemic rickets.Primary cultures of renal epithelial cells from X-linked hypophosphatemic (Hyp) mice express defects in phosphate transport and vitamin D metabolismFibroblast growth factor 23 regulates renal 1,25-dihydroxyvitamin D and phosphate metabolism via the MAP kinase signaling pathway in Hyp miceGenetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-null animals.Crosstransplantation of kidneys in normal and Hyp mice. Evidence that the Hyp mouse phenotype is unrelated to an intrinsic renal defectLoss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.Molecular characterisation of the Hyp deletion and an improved assay for its detection.X-linked hypophosphatemia (familial or sex-linked vitamin-D-resistant rickets). X-linked hypophosphatemic (Hyp) mice.Cytogenetic approaches to mouse models of human genetic diseases.Chronic inhibition of ERK1/2 signaling improves disordered bone and mineral metabolism in hypophosphatemic (Hyp) mice.Phosphate: known and potential roles during development and regeneration of teeth and supporting structures.Correction of proximal tubule phosphate transport defect in Hyp mice in vivo and in vitro with indomethacin.
P2860
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P2860
Hypophosphatemia: mouse model for human familial hypophosphatemic (vitamin D-resistant) rickets.
description
1976 nî lūn-bûn
@nan
1976 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1976 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1976年の論文
@ja
1976年論文
@yue
1976年論文
@zh-hant
1976年論文
@zh-hk
1976年論文
@zh-mo
1976年論文
@zh-tw
1976年论文
@wuu
name
Hypophosphatemia: mouse model ...... (vitamin D-resistant) rickets.
@en
type
label
Hypophosphatemia: mouse model ...... (vitamin D-resistant) rickets.
@en
prefLabel
Hypophosphatemia: mouse model ...... (vitamin D-resistant) rickets.
@en
P2093
P2860
P356
P1476
Hypophosphatemia: mouse model ...... (vitamin D-resistant) rickets.
@en
P2093
Glorieux FH
Southard JL
P2860
P304
P356
10.1073/PNAS.73.12.4667
P407
P577
1976-12-01T00:00:00Z