Identification of the di-pyridyl ketone isonicotinoyl hydrazone (PKIH) analogues as potent iron chelators and anti-tumour agents.
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Iron, human growth, and the global epidemic of obesityIron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH)A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics.Exploring the anti-cancer activity of novel thiosemicarbazones generated through the combination of retro-fragments: dissection of critical structure-activity relationships.Structure-activity relationships of novel salicylaldehyde isonicotinoyl hydrazone (SIH) analogs: iron chelation, anti-oxidant and cytotoxic properties.Targeting cancer by binding iron: Dissecting cellular signaling pathwaysCell permeable iron chelators as potential cancer chemotherapeutic agents.Iron deprivation in cancer--potential therapeutic implicationsSynthetic and natural iron chelators: therapeutic potential and clinical useThe novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms.Anti-plasmodial activity of aroylhydrazone and thiosemicarbazone iron chelators: effect on erythrocyte membrane integrity, parasite development and the intracellular labile iron poolThiosemicarbazones: the new wave in cancer treatment.Investigation of the cytotoxic implications of metal chelators against melanoma and approaches to improve the cytotoxicity profiles of metal coordinating agents.Analysis of the Interaction of Dp44mT with Human Serum Albumin and Calf Thymus DNA Using Molecular Docking and Spectroscopic TechniquesThe cytotoxicity of benzaldehyde nitrogen mustard-2-pyridine carboxylic acid hydrazone being involved in topoisomerase IIα inhibition.Piperazinyl fragment improves anticancer activity of Triapine.
P2860
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P2860
Identification of the di-pyridyl ketone isonicotinoyl hydrazone (PKIH) analogues as potent iron chelators and anti-tumour agents.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Identification of the di-pyrid ...... lators and anti-tumour agents.
@en
type
label
Identification of the di-pyrid ...... lators and anti-tumour agents.
@en
prefLabel
Identification of the di-pyrid ...... lators and anti-tumour agents.
@en
P2093
P2860
P356
P1476
Identification of the di-pyrid ...... lators and anti-tumour agents.
@en
P2093
David B Lovejoy
Des R Richardson
Erika M Becker
Judith M Greer
Ralph Watts
P2860
P304
P356
10.1038/SJ.BJP.0705089
P407
P577
2003-03-01T00:00:00Z