Circadian rhythm of dihydrouracil/uracil ratios in biological fluids: a potential biomarker for dihydropyrimidine dehydrogenase levels.
about
Pretherapeutic uracil and dihydrouracil levels of colorectal cancer patients are associated with sex and toxic side effects during adjuvant 5-fluorouracil-based chemotherapy.Investigation by imaging mass spectrometry of biomarker candidates for aging in the hair cortex.LC-MS/MS method for simultaneous analysis of uracil, 5,6-dihydrouracil, 5-fluorouracil and 5-fluoro-5,6-dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patients.Evaluation of predictive tests for screening for dihydropyrimidine dehydrogenase deficiency.A Critical Review on Clinical Application of Separation Techniques for Selective Recognition of Uracil and 5-Fluorouracil.Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteersA simple and rapid high-performance liquid chromatographic (HPLC) method for 5-fluorouracil (5-FU) assay in plasma and possible detection of patients with impaired dihydropyrimidine dehydrogenase (DPD) activity.Important role of the dihydrouracil/uracil ratio in marked interpatient variations of fluoropyrimidine pharmacokinetics and pharmacodynamics.Indirect assessment of dihydropyrimidine dehydrogenase activity in cats.A predictive biomarker for altered 5-fluorouracil pharmacokinetics following repeated administration in a rat model of colorectal cancer.Pharmacokinetics of 5-fluorouracil and increased hepatic dihydropyrimidine dehydrogenase activity levels in 1,2-dimethylhydrazine-induced colorectal cancer model rats.Population Pharmacokinetic-Pharmacodynamic Modeling of 5-Fluorouracil for Toxicities in Rats.Population pharmacokinetic modelling and simulation of 5-fluorouracil incorporating a circadian rhythm in rats.Pharmacokinetics of continuous transarterial infusion of 5-fluorouracil in patients with advanced hepatocellular carcinoma.Individualization of 5-Fluorouracil in the Treatment of Colorectal Cancer
P2860
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P2860
Circadian rhythm of dihydrouracil/uracil ratios in biological fluids: a potential biomarker for dihydropyrimidine dehydrogenase levels.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Circadian rhythm of dihydroura ...... rimidine dehydrogenase levels.
@en
type
label
Circadian rhythm of dihydroura ...... rimidine dehydrogenase levels.
@en
prefLabel
Circadian rhythm of dihydroura ...... rimidine dehydrogenase levels.
@en
P2093
P2860
P356
P1476
Circadian rhythm of dihydroura ...... rimidine dehydrogenase levels.
@en
P2093
P2860
P304
P356
10.1038/SJ.BJP.0705651
P407
P577
2004-01-26T00:00:00Z