Effects of minocycline on Fas-mediated fulminant hepatitis in mice
about
Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocyclineMitochondrial calcium and the permeability transition in cell deathMinocycline chelates Ca2+, binds to membranes, and depolarizes mitochondria by formation of Ca2+-dependent ion channels.Minocycline and doxycycline, but not tetracycline, mitigate liver and kidney injury after hemorrhagic shock/resuscitationMinocycline decreases liver injury after hemorrhagic shock and resuscitation in miceMinocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition.Minocycline as a potential therapeutic agent in neurodegenerative disorders characterised by protein misfoldingMinocycline accelerates hypoxia-inducible factor-1 alpha degradation and inhibits hypoxia-induced neovasculogenesis through prolyl hydroxylase, von Hippel-Lindau-dependent pathway.Minocycline inhibits cell death and decreases mutant Huntingtin aggregation by targeting Apaf-1.Pyruvate dehydrogenase complex and lactate dehydrogenase as targets for therapy of acute liver failure.Hepatocellular apoptosis in mice is associated with early upregulation of mitochondrial glucose metabolism.
P2860
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P2860
Effects of minocycline on Fas-mediated fulminant hepatitis in mice
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Effects of minocycline on Fas-mediated fulminant hepatitis in mice
@en
type
label
Effects of minocycline on Fas-mediated fulminant hepatitis in mice
@en
prefLabel
Effects of minocycline on Fas-mediated fulminant hepatitis in mice
@en
P2093
P2860
P356
P1476
Effects of minocycline on Fas-mediated fulminant hepatitis in mice
@en
P2093
Ching-Len Liao
Heng-Cheng Chu
Huey-Kang Sytwu
Shin-Hua Lin
You-Chen Chao
P2860
P304
P356
10.1038/SJ.BJP.0706079
P407
P50
P577
2005-01-01T00:00:00Z